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Isobaric metabolite interferences and the requirement for close examination of raw data in addition to stringent chromatographic separations in liquid chromatography/tandem mass spectrometric analysis of drugs in biological matrix.
Yan Z, Maher N, Torres R, Cotto C, Hastings B, Dasgupta M, Hyman R, Huebert N, Caldwell GW. Yan Z, et al. Among authors: dasgupta m. Rapid Commun Mass Spectrom. 2008 Jul;22(13):2021-8. doi: 10.1002/rcm.3577. Rapid Commun Mass Spectrom. 2008. PMID: 18512848
Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif.
Kreutter KD, Lu T, Lee L, Giardino EC, Patel S, Huang H, Xu G, Fitzgerald M, Haertlein BJ, Mohan V, Crysler C, Eisennagel S, Dasgupta M, McMillan M, Spurlino JC, Huebert ND, Maryanoff BE, Tomczuk BE, Damiano BP, Player MR. Kreutter KD, et al. Among authors: dasgupta m. Bioorg Med Chem Lett. 2008 May 1;18(9):2865-70. doi: 10.1016/j.bmcl.2008.03.087. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18420408
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.
Qiao L, Baumann CA, Crysler CS, Ninan NS, Abad MC, Spurlino JC, Desjarlais RL, Kervinen J, Neeper MP, Bayoumy SS, Williams R, Deckman IC, Dasgupta M, Reed RL, Huebert ND, Tomczuk BE, Moriarty KJ. Qiao L, et al. Among authors: dasgupta m. Bioorg Med Chem Lett. 2006 Jan 1;16(1):123-8. doi: 10.1016/j.bmcl.2005.09.037. Epub 2005 Oct 19. Bioorg Med Chem Lett. 2006. PMID: 16236500
Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors.
Tomczuk B, Lu T, Soll RM, Fedde C, Wang A, Murphy L, Crysler C, Dasgupta M, Eisennagel S, Spurlino J, Bone R. Tomczuk B, et al. Among authors: dasgupta m. Bioorg Med Chem Lett. 2003 Apr 17;13(8):1495-8. doi: 10.1016/s0960-894x(03)00125-2. Bioorg Med Chem Lett. 2003. PMID: 12668020
321 results