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Hypothesis-driven screening.
Schopfer U, Engeloch C, Höhn F, Mees H, Leeds J, Glickman F, Scheel G, Ferrand S, Fekkes P, Pfeifer M. Schopfer U, et al. Methods Mol Biol. 2009;575:297-316. doi: 10.1007/978-1-60761-274-2_13. Methods Mol Biol. 2009. PMID: 19727621
Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection.
Jacoby E, Schuffenhauer A, Popov M, Azzaoui K, Havill B, Schopfer U, Engeloch C, Stanek J, Acklin P, Rigollier P, Stoll F, Koch G, Meier P, Orain D, Giger R, Hinrichs J, Malagu K, Zimmermann J, Roth HJ. Jacoby E, et al. Among authors: schopfer u. Curr Top Med Chem. 2005;5(4):397-411. doi: 10.2174/1568026053828376. Curr Top Med Chem. 2005. PMID: 15892682 Review.
The Novartis compound archive -- from concept to reality.
Schopfer U, Engeloch C, Stanek J, Girod M, Schuffenhauer A, Jacoby E, Acklin P. Schopfer U, et al. Comb Chem High Throughput Screen. 2005 Sep;8(6):513-9. doi: 10.2174/1386207054867328. Comb Chem High Throughput Screen. 2005. PMID: 16178810
Stability of screening compounds in wet DMSO.
Engeloch C, Schopfer U, Muckenschnabel I, Le Goff F, Mees H, Boesch K, Popov M. Engeloch C, et al. Among authors: schopfer u. J Biomol Screen. 2008 Dec;13(10):999-1006. doi: 10.1177/1087057108326536. Epub 2008 Nov 21. J Biomol Screen. 2008. PMID: 19029012
High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor.
Groot-Kormelink PJ, Ferrand S, Kelley N, Bill A, Freuler F, Imbert PE, Marelli A, Gerwin N, Sivilotti LG, Miraglia L, Orth AP, Oakeley EJ, Schopfer U, Siehler S. Groot-Kormelink PJ, et al. Among authors: schopfer u. PLoS One. 2016 Sep 20;11(9):e0163129. doi: 10.1371/journal.pone.0163129. eCollection 2016. PLoS One. 2016. PMID: 27649498 Free PMC article.
24 results