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Therapeutic vaccination with an interleukin-2-interferon-gamma-secreting allogeneic tumor vaccine in patients with progressive castration-resistant prostate cancer: a phase I/II trial.
Brill TH, Kübler HR, Pohla H, Buchner A, Fend F, Schuster T, van Randenborgh H, Paul R, Kummer T, Plank C, Eisele B, Breul J, Hartung R, Schendel DJ, Gansbacher B. Brill TH, et al. Among authors: schendel dj. Hum Gene Ther. 2009 Dec;20(12):1641-51. doi: 10.1089/hum.2009.101. Hum Gene Ther. 2009. PMID: 19671000 Clinical Trial.
Phase 1 trial of allogeneic gene-modified tumor cell vaccine RCC-26/CD80/IL-2 in patients with metastatic renal cell carcinoma.
Buchner A, Pohla H, Willimsky G, Frankenberger B, Frank R, Baur-Melnyk A, Siebels M, Stief CG, Hofstetter A, Kopp J, Pezzutto A, Blankenstein T, Oberneder R, Schendel DJ. Buchner A, et al. Among authors: schendel dj. Hum Gene Ther. 2010 Mar;21(3):285-97. doi: 10.1089/hum.2008.192. Hum Gene Ther. 2010. PMID: 19788391 Clinical Trial.
Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.
Westermann J, Flörcken A, Willimsky G, van Lessen A, Kopp J, Takvorian A, Jöhrens K, Lukowsky A, Schönemann C, Sawitzki B, Pohla H, Frank R, Dörken B, Schendel DJ, Blankenstein T, Pezzutto A. Westermann J, et al. Among authors: schendel dj. Gene Ther. 2011 Apr;18(4):354-63. doi: 10.1038/gt.2010.143. Epub 2010 Nov 11. Gene Ther. 2011. PMID: 21068778 Clinical Trial.
High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination.
Pohla H, Buchner A, Stadlbauer B, Frankenberger B, Stevanovic S, Walter S, Frank R, Schwachula T, Olek S, Kopp J, Willimsky G, Stief CG, Hofstetter A, Pezzutto A, Blankenstein T, Oberneder R, Schendel DJ. Pohla H, et al. Among authors: schendel dj. Mol Med. 2013 Feb 8;18(1):1499-508. doi: 10.2119/molmed.2012.00221. Mol Med. 2013. PMID: 23269976 Free PMC article. Clinical Trial.
188 results