Gómez-Lechón MJ - Search Results

1

Sequential hepatogenic transdifferentiation of adipose tissue-derived stem cells: relevance of different extracellular signaling molecules, transcription factors involved, and expression of new key marker genes.

Bonora-Centelles A, Jover R, Mirabet V, Lahoz A, Carbonell F, Castell JV, Gómez-Lechón MJ. Bonora-Centelles A, et al. Cell Transplant. 2009;18(12):1319-40. doi: 10.3727/096368909X12483162197321. Epub 2009 Aug 5. Cell Transplant. 2009. PMID: 19660180 Free article.

2

Influence of platelet lysate on the recovery and metabolic performance of cryopreserved human hepatocytes upon thawing.

Tolosa L, Bonora-Centelles A, Donato MT, Mirabet V, Pareja E, Negro A, López S, Castell JV, Gómez-Lechón MJ. Tolosa L, et al. Transplantation. 2011 Jun 27;91(12):1340-6. doi: 10.1097/TP.0b013e31821aba37. Transplantation. 2011. PMID: 21516066

3

Neonatal livers: a source for the isolation of good-performing hepatocytes for cell transplantation.

Tolosa L, Pareja-Ibars E, Donato MT, Cortés M, López S, Jiménez N, Mir J, Castell JV, Gómez-Lechón MJ. Tolosa L, et al. Cell Transplant. 2014;23(10):1229-42. doi: 10.3727/096368913X669743. Epub 2013 Jun 25. Cell Transplant. 2014. PMID: 23803290 Free article.

4

Human mesenchymal stem cells from adipose tissue: Differentiation into hepatic lineage.

Taléns-Visconti R, Bonora A, Jover R, Mirabet V, Carbonell F, Castell JV, Gómez-Lechón MJ. Taléns-Visconti R, et al. Toxicol In Vitro. 2007 Mar;21(2):324-9. doi: 10.1016/j.tiv.2006.08.009. Epub 2006 Sep 5. Toxicol In Vitro. 2007. PMID: 17045453

5

Functional characterization of hepatocytes for cell transplantation: customized cell preparation for each receptor.

Bonora-Centelles A, Donato MT, Lahoz A, Pareja E, Mir J, Castell JV, Gómez-Lechón MJ. Bonora-Centelles A, et al. Cell Transplant. 2010;19(1):21-8. doi: 10.3727/096368909X474267. Cell Transplant. 2010. PMID: 19796502 Free article.

6

Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involved.

Jover R, Bort R, Gómez-Lechón MJ, Castell JV. Jover R, et al. FASEB J. 2002 Nov;16(13):1799-801. doi: 10.1096/fj.02-0195fje. Epub 2002 Sep 19. FASEB J. 2002. PMID: 12354697

7

Role of hepatocyte nuclear factor 3 gamma in the expression of human CYP2C genes.

Bort R, Gómez-Lechón MJ, Castell JV, Jover R. Bort R, et al. Arch Biochem Biophys. 2004 Jun 1;426(1):63-72. doi: 10.1016/j.abb.2004.03.032. Arch Biochem Biophys. 2004. PMID: 15130783

8

Transcriptional regulation of the human hepatic CYP3A4: identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein).

Martínez-Jiménez CP, Gómez-Lechón MJ, Castell JV, Jover R. Martínez-Jiménez CP, et al. Mol Pharmacol. 2005 Jun;67(6):2088-101. doi: 10.1124/mol.104.008169. Epub 2005 Mar 18. Mol Pharmacol. 2005. PMID: 15778453

9

[Alternative sources of hepatocytes for cell therapy].

Taléns-Visconti R, Bonora-Centelles A, Castell JV, Gómez-Lechón MJ. Taléns-Visconti R, et al. Gastroenterol Hepatol. 2006 Jun-Jul;29(6):366-76. doi: 10.1157/13089719. Gastroenterol Hepatol. 2006. PMID: 16790188 Review. Spanish.

10

Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.

Martínez-Jiménez CP, Castell JV, Gómez-Lechón MJ, Jover R. Martínez-Jiménez CP, et al. Mol Pharmacol. 2006 Nov;70(5):1681-92. doi: 10.1124/mol.106.025403. Epub 2006 Aug 1. Mol Pharmacol. 2006. PMID: 16882880

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