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Drug resistance-associated changes in sphingolipids and ABC transporters occur in different regions of membrane domains.
Hinrichs JW, Klappe K, van Riezen M, Kok JW. Hinrichs JW, et al. Among authors: klappe k. J Lipid Res. 2005 Nov;46(11):2367-76. doi: 10.1194/jlr.M500070-JLR200. Epub 2005 Sep 8. J Lipid Res. 2005. PMID: 16150833 Free article.
We have recently shown that two ATP binding cassette (ABC) transporters are enriched in Lubrol-resistant noncaveolar membrane domains in multidrug-resistant human cancer cells [Hinrichs, J. W. J., K. Klappe, I. Hummel, and J. W. Kok. 2004. ATP-binding cassette trans …
We have recently shown that two ATP binding cassette (ABC) transporters are enriched in Lubrol-resistant noncaveolar membrane domains in mul …
The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption.
Meszaros P, Hummel I, Klappe K, Draghiciu O, Hoekstra D, Kok JW. Meszaros P, et al. Among authors: klappe k. Biochim Biophys Acta. 2013 Feb;1828(2):340-51. doi: 10.1016/j.bbamem.2012.10.007. Epub 2012 Oct 17. Biochim Biophys Acta. 2013. PMID: 23085402 Free article.
Previously we have shown that the activity of the multidrug transporter ABCC1 (multidrug resistance protein 1), and its localization in lipid rafts, depends on cortical actin (Hummel I, Klappe K, Ercan C, Kok JW. Mol. Pharm. 2011 79, 229-40). Here we show that the e …
Previously we have shown that the activity of the multidrug transporter ABCC1 (multidrug resistance protein 1), and its localization in lipi …
Long term myriocin treatment increases MRP1 transport activity.
Meszaros P, Klappe K, van Dam A, Ivanova PT, Milne SB, Myers DS, Brown HA, Permentier H, Hoekstra D, Kok JW. Meszaros P, et al. Among authors: klappe k. Int J Biochem Cell Biol. 2013 Feb;45(2):326-34. doi: 10.1016/j.biocel.2012.11.009. Epub 2012 Nov 23. Int J Biochem Cell Biol. 2013. PMID: 23178537 Free PMC article.
44 results