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2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
Van Quaquebeke E, Mahieu T, Dumont P, Dewelle J, Ribaucour F, Simon G, Sauvage S, Gaussin JF, Tuti J, El Yazidi M, Van Vynckt F, Mijatovic T, Lefranc F, Darro F, Kiss R. Van Quaquebeke E, et al. Among authors: dewelle j. J Med Chem. 2007 Aug 23;50(17):4122-34. doi: 10.1021/jm070315q. Epub 2007 Jul 21. J Med Chem. 2007. PMID: 17658777
Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses.
Van Quaquebeke E, Simon G, André A, Dewelle J, El Yazidi M, Bruyneel F, Tuti J, Nacoulma O, Guissou P, Decaestecker C, Braekman JC, Kiss R, Darro F. Van Quaquebeke E, et al. Among authors: dewelle j. J Med Chem. 2005 Feb 10;48(3):849-56. doi: 10.1021/jm049405a. J Med Chem. 2005. PMID: 15689169
IR spectroscopy as a new tool for evidencing antitumor drug signatures.
Gasper R, Dewelle J, Kiss R, Mijatovic T, Goormaghtigh E. Gasper R, et al. Among authors: dewelle j. Biochim Biophys Acta. 2009 Jun;1788(6):1263-70. doi: 10.1016/j.bbamem.2009.02.016. Epub 2009 Feb 27. Biochim Biophys Acta. 2009. PMID: 19250921 Free article.
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