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The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase.
Pluquet O, North S, Bhoumik A, Dimas K, Ronai Z, Hainaut P. Pluquet O, et al. Among authors: north s. J Biol Chem. 2003 Apr 4;278(14):11879-87. doi: 10.1074/jbc.M207396200. Epub 2003 Jan 16. J Biol Chem. 2003. PMID: 12531896 Free article.
WR1065 is an aminothiol with selective cytoprotective effects in normal cells compared with cancer cells. In a previous study (North, S., El-Ghissassi, F., Pluquet, O., Verhaegh, G., and Hainaut, P. (2000) Oncogene 19, 1206-1214), we have shown that WR1065 activates …
WR1065 is an aminothiol with selective cytoprotective effects in normal cells compared with cancer cells. In a previous study (North, …
Regulation of E2F-1 gene expression in avian cells.
Espanel X, Le Cam L, North S, Sardet C, Brun G, Gillet G. Espanel X, et al. Among authors: north s. Oncogene. 1998 Aug 6;17(5):585-94. doi: 10.1038/sj.onc.1201962. Oncogene. 1998. PMID: 9704924
460 results