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Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
Simoni D, Gebbia N, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Provera S, Marchioro C, Tolomeo M, Marinelli L, Limongelli V, Novellino E, Kwaasi A, Dunford J, Buccheri S, Caccamo N, Dieli F. Simoni D, et al. Among authors: gebbia n. J Med Chem. 2008 Nov 13;51(21):6800-7. doi: 10.1021/jm801003y. Epub 2008 Oct 21. J Med Chem. 2008. PMID: 18937434
Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells.
Tolomeo M, Grimaudo S, Di Cristina A, Roberti M, Pizzirani D, Meli M, Dusonchet L, Gebbia N, Abbadessa V, Crosta L, Barucchello R, Grisolia G, Invidiata F, Simoni D. Tolomeo M, et al. Among authors: gebbia n. Int J Biochem Cell Biol. 2005 Aug;37(8):1709-26. doi: 10.1016/j.biocel.2005.03.004. Epub 2005 Apr 26. Int J Biochem Cell Biol. 2005. PMID: 15878840
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines.
Simoni D, Grisolia G, Giannini G, Roberti M, Rondanin R, Piccagli L, Baruchello R, Rossi M, Romagnoli R, Invidiata FP, Grimaudo S, Jung MK, Hamel E, Gebbia N, Crosta L, Abbadessa V, Di Cristina A, Dusonchet L, Meli M, Tolomeo M. Simoni D, et al. Among authors: gebbia n. J Med Chem. 2005 Feb 10;48(3):723-36. doi: 10.1021/jm049622b. J Med Chem. 2005. PMID: 15689156
Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells.
Simoni D, Giannini G, Roberti M, Rondanin R, Baruchello R, Rossi M, Grisolia G, Invidiata FP, Aiello S, Marino S, Cavallini S, Siniscalchi A, Gebbia N, Crosta L, Grimaudo S, Abbadessa V, Di Cristina A, Tolomeo M. Simoni D, et al. Among authors: gebbia n. J Med Chem. 2005 Jun 30;48(13):4293-9. doi: 10.1021/jm049080y. J Med Chem. 2005. PMID: 15974583
Stilbene-based anticancer agents: resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism.
Simoni D, Roberti M, Invidiata FP, Aiello E, Aiello S, Marchetti P, Baruchello R, Eleopra M, Di Cristina A, Grimaudo S, Gebbia N, Crosta L, Dieli F, Tolomeo M. Simoni D, et al. Among authors: gebbia n. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3245-8. doi: 10.1016/j.bmcl.2006.03.028. Epub 2006 Mar 31. Bioorg Med Chem Lett. 2006. PMID: 16580204
179 results