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Rotigaptide (ZP123) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs.
Hennan JK, Swillo RE, Morgan GA, Keith JC Jr, Schaub RG, Smith RP, Feldman HS, Haugan K, Kantrowitz J, Wang PJ, Abu-Qare A, Butera J, Larsen BD, Crandall DL. Hennan JK, et al. Among authors: feldman hs. J Pharmacol Exp Ther. 2006 Apr;317(1):236-43. doi: 10.1124/jpet.105.096933. Epub 2005 Dec 12. J Pharmacol Exp Ther. 2006. PMID: 16344331
The gap junction modifier, GAP-134 [(2S,4R)-1-(2-aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic acid], improves conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model.
Rossman EI, Liu K, Morgan GA, Swillo RE, Krueger JA, Gardell SJ, Butera J, Gruver M, Kantrowitz J, Feldman HS, Petersen JS, Haugan K, Hennan JK. Rossman EI, et al. Among authors: feldman hs. J Pharmacol Exp Ther. 2009 Jun;329(3):1127-33. doi: 10.1124/jpet.108.150102. Epub 2009 Feb 27. J Pharmacol Exp Ther. 2009. PMID: 19252062
Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children.
Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Newton KP, et al. Among authors: feldman hs. J Pediatr. 2017 Aug;187:141-146.e1. doi: 10.1016/j.jpeds.2017.03.007. Epub 2017 Mar 30. J Pediatr. 2017. PMID: 28366357 Free PMC article.
International Life Sciences Institute (Health and Environmental Sciences Institute, HESI) initiative on moving towards better predictors of drug-induced torsades de pointes.
Bass AS, Darpo B, Breidenbach A, Bruse K, Feldman HS, Garnes D, Hammond T, Haverkamp W, January C, Koerner J, Lawrence C, Leishman D, Roden D, Valentin JP, Vos MA, Zhou YY, Karluss T, Sager P. Bass AS, et al. Among authors: feldman hs. Br J Pharmacol. 2008 Aug;154(7):1491-501. doi: 10.1038/bjp.2008.279. Br J Pharmacol. 2008. PMID: 18663380 Free PMC article.
Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics.
Vargas HM, Bass AS, Breidenbach A, Feldman HS, Gintant GA, Harmer AR, Heath B, Hoffmann P, Lagrutta A, Leishman D, McMahon N, Mittelstadt S, Polonchuk L, Pugsley MK, Salata JJ, Valentin JP. Vargas HM, et al. Among authors: feldman hs. J Pharmacol Toxicol Methods. 2008 Sep-Oct;58(2):72-6. doi: 10.1016/j.vascn.2008.04.001. Epub 2008 Apr 18. J Pharmacol Toxicol Methods. 2008. PMID: 18508287
65 results