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Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.
Pringle DR, Vasko VV, Yu L, Manchanda PK, Lee AA, Zhang X, Kirschner JM, Parlow AF, Saji M, Jarjoura D, Ringel MD, La Perle KM, Kirschner LS. Pringle DR, et al. Among authors: kirschner ls, kirschner jm. J Clin Endocrinol Metab. 2014 May;99(5):E804-12. doi: 10.1210/jc.2013-3101. Epub 2014 Feb 10. J Clin Endocrinol Metab. 2014. PMID: 24512487 Free PMC article.
BRAF activates and physically interacts with PAK to regulate cell motility.
McCarty SK, Saji M, Zhang X, Knippler CM, Kirschner LS, Fernandez S, Ringel MD. McCarty SK, et al. Among authors: kirschner ls. Endocr Relat Cancer. 2014;21(6):865-77. doi: 10.1530/ERC-14-0424. Epub 2014 Sep 16. Endocr Relat Cancer. 2014. PMID: 25228413 Free PMC article.
113 results