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Precise genome modification in the crop species Zea mays using zinc-finger nucleases.
Shukla VK, Doyon Y, Miller JC, DeKelver RC, Moehle EA, Worden SE, Mitchell JC, Arnold NL, Gopalan S, Meng X, Choi VM, Rock JM, Wu YY, Katibah GE, Zhifang G, McCaskill D, Simpson MA, Blakeslee B, Greenwalt SA, Butler HJ, Hinkley SJ, Zhang L, Rebar EJ, Gregory PD, Urnov FD. Shukla VK, et al. Among authors: gopalan s. Nature. 2009 May 21;459(7245):437-41. doi: 10.1038/nature07992. Epub 2009 Apr 29. Nature. 2009. PMID: 19404259
Transcriptional activation of Brassica napus β-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor.
Gupta M, DeKelver RC, Palta A, Clifford C, Gopalan S, Miller JC, Novak S, Desloover D, Gachotte D, Connell J, Flook J, Patterson T, Robbins K, Rebar EJ, Gregory PD, Urnov FD, Petolino JF. Gupta M, et al. Among authors: gopalan s. Plant Biotechnol J. 2012 Sep;10(7):783-91. doi: 10.1111/j.1467-7652.2012.00695.x. Epub 2012 Apr 23. Plant Biotechnol J. 2012. PMID: 22520333 Free article.
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, Sun HC, Pitz KJ, Rock JM, Zhang L, Davis GD, Rebar EJ, Cheeseman IM, Yamamoto KR, Sabatini DM, Jaenisch R, Gregory PD, Urnov FD. DeKelver RC, et al. Genome Res. 2010 Aug;20(8):1133-42. doi: 10.1101/gr.106773.110. Epub 2010 May 27. Genome Res. 2010. PMID: 20508142 Free PMC article.
PRMT5 orchestrates EGFR and AKT networks to activate NFκB and promote EMT.
Huang L, Ravi M, Zhang XO, Verdejo-Torres O, Shendy NAM, Nezhady MAM, Gopalan S, Wang G, Durbin AD, Fazzio TG, Wu Q. Huang L, et al. Among authors: gopalan s. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.574104. doi: 10.1101/2024.01.03.574104. bioRxiv. 2024. PMID: 38260418 Free PMC article. Preprint.
234 results