Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action.
Kasparkova J, Novakova O, Marini V, Najajreh Y, Gibson D, Perez JM, Brabec V.
Kasparkova J, et al. Among authors: brabec v.
J Biol Chem. 2003 Nov 28;278(48):47516-25. doi: 10.1074/jbc.M304720200. Epub 2003 Sep 10.
J Biol Chem. 2003.
PMID: 12970368
Free article.
To this end, however, several new complexes of the trans structure have been identified that exhibit cytotoxicity in tumor cells that is even better than that of the analogous cis isomers. We reported recently (Kasparkova, J., Marini, V., Najajreh, Y., Gibson, D., and B …
To this end, however, several new complexes of the trans structure have been identified that exhibit cytotoxicity in tumor cells that is eve …