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Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action.
Kasparkova J, Novakova O, Marini V, Najajreh Y, Gibson D, Perez JM, Brabec V. Kasparkova J, et al. Among authors: brabec v. J Biol Chem. 2003 Nov 28;278(48):47516-25. doi: 10.1074/jbc.M304720200. Epub 2003 Sep 10. J Biol Chem. 2003. PMID: 12970368 Free article.
To this end, however, several new complexes of the trans structure have been identified that exhibit cytotoxicity in tumor cells that is even better than that of the analogous cis isomers. We reported recently (Kasparkova, J., Marini, V., Najajreh, Y., Gibson, D., and B
To this end, however, several new complexes of the trans structure have been identified that exhibit cytotoxicity in tumor cells that is eve …
Molecular aspects of antitumor effects of a new platinum(IV) drug.
Kaspárková J, Nováková O, Vrána O, Intini F, Natile G, Brabec V. Kaspárková J, et al. Among authors: brabec v. Mol Pharmacol. 2006 Nov;70(5):1708-19. doi: 10.1124/mol.106.027730. Epub 2006 Aug 8. Mol Pharmacol. 2006. PMID: 16896071
453 results