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Activated protein C protects against myocardial ischemia/ reperfusion injury via inhibition of apoptosis and inflammation.
Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1087-92. doi: 10.1161/ATVBAHA.109.188656. Epub 2009 Apr 16.
Arterioscler Thromb Vasc Biol. 2009.
PMID: 19372456
Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice.
Loubele ST, Spek CA, Leenders P, van Oerle R, Aberson HL, van der Voort D, Hamulyák K, Petersen LC, Spronk HM, ten Cate H.
Loubele ST, et al.
J Thromb Haemost. 2009 Feb;7(2):290-8. doi: 10.1111/j.1538-7836.2008.03232.x. Epub 2008 Nov 22.
J Thromb Haemost. 2009.
PMID: 19036066
Free article.
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Activated protein C: a promising drug with multiple effects?
Loubele ST, Spronk HM, Ten Cate H.
Loubele ST, et al.
Mini Rev Med Chem. 2009 May;9(5):620-6. doi: 10.2174/138955709788167547.
Mini Rev Med Chem. 2009.
PMID: 19456292
Review.
Item in Clipboard
Anticoagulant therapy in critical organ ischaemia/reperfusion injury.
Loubele ST, ten Cate H, Spronk HM.
Loubele ST, et al.
Thromb Haemost. 2010 Jul;104(1):136-42. doi: 10.1160/TH09-08-0582. Epub 2010 Apr 29.
Thromb Haemost. 2010.
PMID: 20431846
Review.
Item in Clipboard
Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner.
Borissoff JI, Otten JJ, Heeneman S, Leenders P, van Oerle R, Soehnlein O, Loubele ST, Hamulyák K, Hackeng TM, Daemen MJ, Degen JL, Weiler H, Esmon CT, van Ryn J, Biessen EA, Spronk HM, ten Cate H.
Borissoff JI, et al. Among authors: loubele st.
PLoS One. 2013;8(2):e55784. doi: 10.1371/journal.pone.0055784. Epub 2013 Feb 7.
PLoS One. 2013.
PMID: 23409043
Free PMC article.
Item in Clipboard
Preanalytic variables of thrombin generation: towards a standard procedure and validation of the method.
Loeffen R, Kleinegris MC, Loubele ST, Pluijmen PH, Fens D, van Oerle R, ten Cate H, Spronk HM.
Loeffen R, et al. Among authors: loubele st.
J Thromb Haemost. 2012 Dec;10(12):2544-54. doi: 10.1111/jth.12012.
J Thromb Haemost. 2012.
PMID: 23020632
Free article.
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Contribution of platelet glycoprotein VI to the thrombogenic effect of collagens in fibrous atherosclerotic lesions.
Cosemans JM, Kuijpers MJ, Lecut C, Loubele ST, Heeneman S, Jandrot-Perrus M, Heemskerk JW.
Cosemans JM, et al. Among authors: loubele st.
Atherosclerosis. 2005 Jul;181(1):19-27. doi: 10.1016/j.atherosclerosis.2004.12.037. Epub 2005 Feb 12.
Atherosclerosis. 2005.
PMID: 15939050
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The structure-function relationship of activated protein C. Lessons from natural and engineered mutations.
Wildhagen KC, Lutgens E, Loubele ST, ten Cate H, Nicolaes GA.
Wildhagen KC, et al. Among authors: loubele st.
Thromb Haemost. 2011 Dec;106(6):1034-45. doi: 10.1160/TH11-08-0522. Epub 2011 Nov 10.
Thromb Haemost. 2011.
PMID: 22072231
Review.
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