Saqcena MK - Search Results

1

Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases.

Galletti M, Riccardo S, Parisi F, Lora C, Saqcena MK, Rivas L, Wong B, Serra A, Serras F, Grifoni D, Pelicci P, Jiang J, Bellosta P. Galletti M, et al. Among authors: saqcena mk. Mol Cell Biol. 2009 Jun;29(12):3424-34. doi: 10.1128/MCB.01535-08. Epub 2009 Apr 13. Mol Cell Biol. 2009. PMID: 19364825 Free PMC article.

2

Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo.

Parisi F, Riccardo S, Daniel M, Saqcena M, Kundu N, Pession A, Grifoni D, Stocker H, Tabak E, Bellosta P. Parisi F, et al. BMC Biol. 2011 Sep 27;9:65. doi: 10.1186/1741-7007-9-65. BMC Biol. 2011. PMID: 21951762 Free PMC article.

3

Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).

Xu L, Salloum D, Medlin PS, Saqcena M, Yellen P, Perrella B, Foster DA. Xu L, et al. J Biol Chem. 2011 Jul 22;286(29):25477-86. doi: 10.1074/jbc.M111.249631. Epub 2011 May 28. J Biol Chem. 2011. PMID: 21622984 Free PMC article.

4

High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.

Yellen P, Saqcena M, Salloum D, Feng J, Preda A, Xu L, Rodrik-Outmezguine V, Foster DA. Yellen P, et al. Cell Cycle. 2011 Nov 15;10(22):3948-56. doi: 10.4161/cc.10.22.18124. Epub 2011 Nov 15. Cell Cycle. 2011. PMID: 22071574 Free PMC article.

5

Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle.

Saqcena M, Menon D, Patel D, Mukhopadhyay S, Chow V, Foster DA. Saqcena M, et al. PLoS One. 2013 Aug 19;8(8):e74157. doi: 10.1371/journal.pone.0074157. eCollection 2013. PLoS One. 2013. PMID: 23977397 Free PMC article.

6

Reciprocal regulation of AMP-activated protein kinase and phospholipase D.

Mukhopadhyay S, Saqcena M, Chatterjee A, Garcia A, Frias MA, Foster DA. Mukhopadhyay S, et al. J Biol Chem. 2015 Mar 13;290(11):6986-93. doi: 10.1074/jbc.M114.622571. Epub 2015 Jan 29. J Biol Chem. 2015. PMID: 25632961 Free PMC article.

7

Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle.

Saqcena M, Patel D, Menon D, Mukhopadhyay S, Foster DA. Saqcena M, et al. Cell Cycle. 2015;14(14):2285-92. doi: 10.1080/15384101.2015.1046653. Epub 2015 May 6. Cell Cycle. 2015. PMID: 25945415 Free PMC article.

8

A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.

Patel D, Salloum D, Saqcena M, Chatterjee A, Mroz V, Ohh M, Foster DA. Patel D, et al. J Biol Chem. 2017 Jan 20;292(3):936-944. doi: 10.1074/jbc.M116.757864. Epub 2016 Dec 12. J Biol Chem. 2017. PMID: 27956548 Free PMC article.

9

EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC.

Krishnamoorthy GP, Davidson NR, Leach SD, Zhao Z, Lowe SW, Lee G, Landa I, Nagarajah J, Saqcena M, Singh K, Wendel HG, Dogan S, Tamarapu PP, Blenis J, Ghossein RA, Knauf JA, Rätsch G, Fagin JA. Krishnamoorthy GP, et al. Cancer Discov. 2019 Feb;9(2):264-281. doi: 10.1158/2159-8290.CD-18-0606. Epub 2018 Oct 10. Cancer Discov. 2019. PMID: 30305285 Free PMC article.

10

Co-inhibition of SMAD and MAPK signaling enhances 124I uptake in BRAF-mutant thyroid cancers.

Luckett KA, Cracchiolo JR, Krishnamoorthy GP, Leandro-Garcia LJ, Nagarajah J, Saqcena M, Lester R, Im SY, Zhao Z, Lowe SW, de Stanchina E, Sherman EJ, Ho AL, Leach SD, Knauf JA, Fagin JA. Luckett KA, et al. Endocr Relat Cancer. 2021 May 18;28(6):391-402. doi: 10.1530/ERC-21-0017. Endocr Relat Cancer. 2021. PMID: 33890869 Free PMC article.

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