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The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.
Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H. Li C, et al. Among authors: lang s. J Clin Invest. 2011 Nov;121(11):4537-47. doi: 10.1172/JCI57850. Epub 2011 Oct 24. J Clin Invest. 2011. PMID: 22019589 Free PMC article.
Platelets in thrombosis and hemostasis: old topic with new mechanisms.
Wang Y, Andrews M, Yang Y, Lang S, Jin JW, Cameron-Vendrig A, Zhu G, Reheman A, Ni H. Wang Y, et al. Among authors: lang s. Cardiovasc Hematol Disord Drug Targets. 2012 Dec;12(2):126-32. doi: 10.2174/1871529x11202020126. Cardiovasc Hematol Disord Drug Targets. 2012. PMID: 23030445 Review.
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia.
Yougbaré I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkić J, Peng C, Höglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H. Yougbaré I, et al. Among authors: lang s. Nat Commun. 2017 Aug 9;8(1):224. doi: 10.1038/s41467-017-00269-1. Nat Commun. 2017. PMID: 28794456 Free PMC article.
Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage.
Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai WS, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen XY, Skogen B, Adamson SL, Freedman J, Ni H. Yougbaré I, et al. Among authors: lang s. J Clin Invest. 2015 Apr;125(4):1545-56. doi: 10.1172/JCI77820. Epub 2015 Mar 16. J Clin Invest. 2015. PMID: 25774504 Free PMC article.
3,095 results