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Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.
Zhang MM, Green BR, Catlin P, Fiedler B, Azam L, Chadwick A, Terlau H, McArthur JR, French RJ, Gulyas J, Rivier JE, Smith BJ, Norton RS, Olivera BM, Yoshikami D, Bulaj G. Zhang MM, et al. Among authors: french rj. J Biol Chem. 2007 Oct 19;282(42):30699-706. doi: 10.1074/jbc.M704616200. Epub 2007 Aug 27. J Biol Chem. 2007. PMID: 17724025 Free article.
Trans-channel interactions in batrachotoxin-modified skeletal muscle sodium channels: voltage-dependent block by cytoplasmic amines, and the influence of mu-conotoxin GIIIA derivatives and permeant ions.
Pavlov E, Britvina T, McArthur JR, Ma Q, Sierralta I, Zamponi GW, French RJ. Pavlov E, et al. Among authors: french rj. Biophys J. 2008 Nov 1;95(9):4277-88. doi: 10.1529/biophysj.108.138297. Epub 2008 Jul 25. Biophys J. 2008. PMID: 18658222 Free PMC article.
Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels.
Cordeiro S, Finol-Urdaneta RK, Köpfer D, Markushina A, Song J, French RJ, Kopec W, de Groot BL, Giacobassi MJ, Leavitt LS, Raghuraman S, Teichert RW, Olivera BM, Terlau H. Cordeiro S, et al. Among authors: french rj. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1059-1064. doi: 10.1073/pnas.1813161116. Epub 2018 Dec 28. Proc Natl Acad Sci U S A. 2019. PMID: 30593566 Free PMC article.
Docking of mu-conotoxin GIIIA in the sodium channel outer vestibule.
Choudhary G, Aliste MP, Tieleman DP, French RJ, Dudley SC Jr. Choudhary G, et al. Among authors: french rj. Channels (Austin). 2007 Sep-Oct;1(5):344-52. doi: 10.4161/chan.5112. Epub 2007 Oct 3. Channels (Austin). 2007. PMID: 18690041 Free PMC article.
Dependence of mu-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]: implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets.
Li RA, Hui K, French RJ, Sato K, Henrikson CA, Tomaselli GF, Marbán E. Li RA, et al. Among authors: french rj. J Biol Chem. 2003 Aug 15;278(33):30912-9. doi: 10.1074/jbc.M301039200. Epub 2003 May 21. J Biol Chem. 2003. PMID: 12764145 Free article.
123 results