Cheetham S - Search Results

1

Receptor occupancy and brain free fraction.

Watson J, Wright S, Lucas A, Clarke KL, Viggers J, Cheetham S, Jeffrey P, Porter R, Read KD. Watson J, et al. Among authors: cheetham s. Drug Metab Dispos. 2009 Apr;37(4):753-60. doi: 10.1124/dmd.108.022814. Epub 2009 Jan 21. Drug Metab Dispos. 2009. PMID: 19158315

2

[3H]nisoxetine--a radioligand for noradrenaline reuptake sites: correlation with inhibition of [3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments.

Cheetham SC, Viggers JA, Butler SA, Prow MR, Heal DJ. Cheetham SC, et al. Neuropharmacology. 1996 Jan;35(1):63-70. doi: 10.1016/0028-3908(95)00134-4. Neuropharmacology. 1996. PMID: 8684598

3

Sibutramine does not decrease the number of 5-HT re-uptake sites in rat brain and, like fluoxetine, protects against the deficits produced by dexfenfluramine.

Cheetham SC, Viggers JA, Slater NA, Heal DJ. Cheetham SC, et al. Neuropharmacology. 2000 Aug 23;39(11):2028-35. doi: 10.1016/s0028-3908(00)00032-0. Neuropharmacology. 2000. PMID: 10963746

4

Synthesis and SAR of 4-aryl-1-(indazol-5-yl)pyridin-2(1H)ones as MCH-1 antagonists for the treatment of obesity.

Hadden M, Deering DM, Henderson AJ, Surman MD, Luche M, Khmelnitsky Y, Vickers S, Viggers J, Cheetham S, Guzzo PR. Hadden M, et al. Among authors: cheetham s. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7020-3. doi: 10.1016/j.bmcl.2010.09.037. Epub 2010 Sep 21. Bioorg Med Chem Lett. 2010. PMID: 20951036

5

[3H]paroxetine binding in rat frontal cortex strongly correlates with [3H]5-HT uptake: effect of administration of various antidepressant treatments.

Cheetham SC, Viggers JA, Slater NA, Heal DJ, Buckett WR. Cheetham SC, et al. Neuropharmacology. 1993 Aug;32(8):737-43. doi: 10.1016/0028-3908(93)90181-2. Neuropharmacology. 1993. PMID: 8413837

6

Tetrahydrocarboline analogs as MCH-1 antagonists.

Henderson AJ, Deering D, Grabowski JF, Hadden M, Jiang X, Khmelnitsky Y, Luche M, Surman MD, Cheetham S, Vickers S, Viggers J, Guzzo PR. Henderson AJ, et al. Among authors: cheetham s. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7024-8. doi: 10.1016/j.bmcl.2010.09.122. Epub 2010 Sep 29. Bioorg Med Chem Lett. 2010. PMID: 20952195

7

5-(pyridinon-1-yl)indazoles and 5-(furopyridinon-5-yl)indazoles as MCH-1 antagonists.

Surman MD, Freeman EE, Grabowski JF, Hadden M, Henderson AJ, Jiang G, Jiang XM, Luche M, Khmelnitsky Y, Vickers S, Viggers J, Cheetham S, Guzzo PR. Surman MD, et al. Among authors: cheetham s. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7015-9. doi: 10.1016/j.bmcl.2010.09.039. Epub 2010 Sep 16. Bioorg Med Chem Lett. 2010. PMID: 20961756

8

Dopamine D1 and D2 receptor binding sites in brain samples from depressed suicides and controls.

Bowden C, Theodorou AE, Cheetham SC, Lowther S, Katona CL, Crompton MR, Horton RW. Bowden C, et al. Among authors: cheetham sc. Brain Res. 1997 Mar 28;752(1-2):227-33. doi: 10.1016/s0006-8993(96)01460-6. Brain Res. 1997. PMID: 9106461

9

Receptor binding and functional evidence suggest that postsynaptic alpha 2-adrenoceptors in rat brain are of the alpha 2D subtype.

Heal DJ, Cheetham SC, Butler SA, Gosden J, Prow MR, Buckett WR. Heal DJ, et al. Among authors: cheetham sc. Eur J Pharmacol. 1995 Apr 24;277(2-3):215-21. doi: 10.1016/0014-2999(95)00078-y. Eur J Pharmacol. 1995. PMID: 7493611

10

The utility of animal models to evaluate novel anti-obesity agents.

Vickers SP, Jackson HC, Cheetham SC. Vickers SP, et al. Br J Pharmacol. 2011 Oct;164(4):1248-62. doi: 10.1111/j.1476-5381.2011.01245.x. Br J Pharmacol. 2011. PMID: 21265828 Free PMC article. Review.

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