Sauer K - Search Results

1

A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function.

Barouch-Bentov R, Che J, Lee CC, Yang Y, Herman A, Jia Y, Velentza A, Watson J, Sternberg L, Kim S, Ziaee N, Miller A, Jackson C, Fujimoto M, Young M, Batalov S, Liu Y, Warmuth M, Wiltshire T, Cooke MP, Sauer K. Barouch-Bentov R, et al. Among authors: sauer k. Mol Cell. 2009 Jan 16;33(1):43-52. doi: 10.1016/j.molcel.2008.12.024. Mol Cell. 2009. PMID: 19150426 Free PMC article.

2

Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity.

Wen BG, Pletcher MT, Warashina M, Choe SH, Ziaee N, Wiltshire T, Sauer K, Cooke MP. Wen BG, et al. Among authors: sauer k. Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5604-9. doi: 10.1073/pnas.0306907101. Epub 2004 Apr 2. Proc Natl Acad Sci U S A. 2004. PMID: 15064401 Free PMC article.

3

Mechanisms of drug resistance in kinases.

Barouch-Bentov R, Sauer K. Barouch-Bentov R, et al. Among authors: sauer k. Expert Opin Investig Drugs. 2011 Feb;20(2):153-208. doi: 10.1517/13543784.2011.546344. Expert Opin Investig Drugs. 2011. PMID: 21235428 Free PMC article. Review.

4

Integrating traditional and postgenomic approaches to investigate lymphocyte development and function.

Huang YH, Barouch-Bentov R, Herman A, Walker J, Sauer K. Huang YH, et al. Among authors: sauer k. Adv Exp Med Biol. 2006;584:245-76. doi: 10.1007/0-387-34132-3_18. Adv Exp Med Biol. 2006. PMID: 16802612 Review. No abstract available.

5

Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

Xu X, Jaeger ER, Wang X, Lagler-Ferrez E, Batalov S, Mathis NL, Wiltshire T, Walker JR, Cooke MP, Sauer K, Huang YH. Xu X, et al. Among authors: sauer k. PLoS One. 2014 Aug 18;9(8):e105561. doi: 10.1371/journal.pone.0105561. eCollection 2014. PLoS One. 2014. PMID: 25133611 Free PMC article.

6

Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation.

Miller AT, Sandberg M, Huang YH, Young M, Sutton S, Sauer K, Cooke MP. Miller AT, et al. Among authors: sauer k. Nat Immunol. 2007 May;8(5):514-21. doi: 10.1038/ni1458. Epub 2007 Apr 8. Nat Immunol. 2007. PMID: 17417640

7

Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B.

Chamberlain PP, Sandberg ML, Sauer K, Cooke MP, Lesley SA, Spraggon G. Chamberlain PP, et al. Among authors: sauer k. Biochemistry. 2005 Nov 8;44(44):14486-93. doi: 10.1021/bi051256q. Biochemistry. 2005. PMID: 16262249

8

Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate.

Sauer K, Cooke MP. Sauer K, et al. Nat Rev Immunol. 2010 Apr;10(4):257-71. doi: 10.1038/nri2745. Nat Rev Immunol. 2010. PMID: 20336153 Free PMC article. Review.

9

Positive regulation of Itk PH domain function by soluble IP4.

Huang YH, Grasis JA, Miller AT, Xu R, Soonthornvacharin S, Andreotti AH, Tsoukas CD, Cooke MP, Sauer K. Huang YH, et al. Among authors: sauer k. Science. 2007 May 11;316(5826):886-9. doi: 10.1126/science.1138684. Epub 2007 Apr 5. Science. 2007. PMID: 17412921

10

Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo.

Tinoco R, Alcalde V, Yang Y, Sauer K, Zuniga EI. Tinoco R, et al. Among authors: sauer k. Immunity. 2009 Jul 17;31(1):145-57. doi: 10.1016/j.immuni.2009.06.015. Immunity. 2009. PMID: 19604493 Free PMC article.

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