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Changes in heparan sulfate are associated with delayed wound repair, altered cell migration, adhesion and contractility in the galactosyltransferase I (beta4GalT-7) deficient form of Ehlers-Danlos syndrome.
Götte M, Spillmann D, Yip GW, Versteeg E, Echtermeyer FG, van Kuppevelt TH, Kiesel L. Götte M, et al. Among authors: spillmann d. Hum Mol Genet. 2008 Apr 1;17(7):996-1009. doi: 10.1093/hmg/ddm372. Epub 2007 Dec 24. Hum Mol Genet. 2008. PMID: 18158310
HS3ST2 modulates breast cancer cell invasiveness via MAP kinase- and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression.
Vijaya Kumar A, Salem Gassar E, Spillmann D, Stock C, Sen YP, Zhang T, Van Kuppevelt TH, Hülsewig C, Koszlowski EO, Pavao MS, Ibrahim SA, Poeter M, Rescher U, Kiesel L, Koduru S, Yip GW, Götte M. Vijaya Kumar A, et al. Among authors: spillmann d. Int J Cancer. 2014 Dec 1;135(11):2579-92. doi: 10.1002/ijc.28921. Epub 2014 Apr 30. Int J Cancer. 2014. PMID: 24752740 Free article.
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.
Abramsson A, Kurup S, Busse M, Yamada S, Lindblom P, Schallmeiner E, Stenzel D, Sauvaget D, Ledin J, Ringvall M, Landegren U, Kjellén L, Bondjers G, Li JP, Lindahl U, Spillmann D, Betsholtz C, Gerhardt H. Abramsson A, et al. Among authors: spillmann d. Genes Dev. 2007 Feb 1;21(3):316-31. doi: 10.1101/gad.398207. Genes Dev. 2007. PMID: 17289920 Free PMC article.
73 results