Carra S - Search Results

1

HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{alpha} phosphorylation.

Carra S, Brunsting JF, Lambert H, Landry J, Kampinga HH. Carra S, et al. J Biol Chem. 2009 Feb 27;284(9):5523-32. doi: 10.1074/jbc.M807440200. Epub 2008 Dec 29. J Biol Chem. 2009. PMID: 19114712 Free article.

2

HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells.

Carra S, Sivilotti M, Chávez Zobel AT, Lambert H, Landry J. Carra S, et al. Hum Mol Genet. 2005 Jun 15;14(12):1659-69. doi: 10.1093/hmg/ddi174. Epub 2005 May 6. Hum Mol Genet. 2005. PMID: 15879436

3

HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.

Carra S, Seguin SJ, Lambert H, Landry J. Carra S, et al. J Biol Chem. 2008 Jan 18;283(3):1437-1444. doi: 10.1074/jbc.M706304200. Epub 2007 Nov 15. J Biol Chem. 2008. PMID: 18006506 Free article.

4

HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy.

Carra S, Seguin SJ, Landry J. Carra S, et al. Autophagy. 2008 Feb;4(2):237-9. doi: 10.4161/auto.5407. Epub 2007 Dec 11. Autophagy. 2008. PMID: 18094623 Review.

5

Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families.

Vos MJ, Hageman J, Carra S, Kampinga HH. Vos MJ, et al. Among authors: carra s. Biochemistry. 2008 Jul 8;47(27):7001-11. doi: 10.1021/bi800639z. Epub 2008 Jun 17. Biochemistry. 2008. PMID: 18557634 Review.

6

The stress-inducible HspB8-Bag3 complex induces the eIF2alpha kinase pathway: implications for protein quality control and viral factory degradation?

Carra S. Carra S. Autophagy. 2009 Apr;5(3):428-9. doi: 10.4161/auto.5.3.7894. Epub 2009 Apr 21. Autophagy. 2009. PMID: 19202352

7

Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction.

Fuchs M, Poirier DJ, Seguin SJ, Lambert H, Carra S, Charette SJ, Landry J. Fuchs M, et al. Among authors: carra s. Biochem J. 2009 Dec 14;425(1):245-55. doi: 10.1042/BJ20090907. Biochem J. 2009. PMID: 19845507

8

Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3).

Sun X, Fontaine JM, Hoppe AD, Carra S, DeGuzman C, Martin JL, Simon S, Vicart P, Welsh MJ, Landry J, Benndorf R. Sun X, et al. Among authors: carra s. Cell Stress Chaperones. 2010 Sep;15(5):567-82. doi: 10.1007/s12192-010-0169-y. Epub 2010 Feb 17. Cell Stress Chaperones. 2010. PMID: 20157854 Free PMC article.

9

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones.

Vos MJ, Zijlstra MP, Kanon B, van Waarde-Verhagen MA, Brunt ER, Oosterveld-Hut HM, Carra S, Sibon OC, Kampinga HH. Vos MJ, et al. Among authors: carra s. Hum Mol Genet. 2010 Dec 1;19(23):4677-93. doi: 10.1093/hmg/ddq398. Epub 2010 Sep 15. Hum Mol Genet. 2010. PMID: 20843828

10

Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.

Carra S, Boncoraglio A, Kanon B, Brunsting JF, Minoia M, Rana A, Vos MJ, Seidel K, Sibon OC, Kampinga HH. Carra S, et al. J Biol Chem. 2010 Nov 26;285(48):37811-22. doi: 10.1074/jbc.M110.127498. Epub 2010 Sep 21. J Biol Chem. 2010. PMID: 20858900 Free PMC article.

In cells, HSPB8 cooperates with BAG3 to stimulate autophagy in an eIF2alpha-dependent manner and facilitates the clearance of aggregate-prone proteins (Carra, S., Seguin, S. J., Lambert, H., and Landry, J. (2008) J. Biol. Chem. 283, 1437-1444; Carra, …

In cells, HSPB8 cooperates with BAG3 to stimulate autophagy in an eIF2alpha-dependent manner and facilitates the clearance of aggregate-pron …

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