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Effect of desvenlafaxine on the cytochrome P450 2D6 enzyme system.
J Psychiatr Pract. 2008 Nov;14(6):368-78. doi: 10.1097/01.pra.0000341891.43501.6b.
J Psychiatr Pract. 2008.
PMID: 19057238
Review.
Comparison of the pharmacokinetics of venlafaxine extended release and desvenlafaxine in extensive and poor cytochrome P450 2D6 metabolizers.
Preskorn S, Patroneva A, Silman H, Jiang Q, Isler JA, Burczynski ME, Ahmed S, Paul J, Nichols AI.
Preskorn S, et al.
J Clin Psychopharmacol. 2009 Feb;29(1):39-43. doi: 10.1097/JCP.0b013e318192e4c1.
J Clin Psychopharmacol. 2009.
PMID: 19142106
Clinical Trial.
Item in Clipboard
An assessment of drug-drug interactions: the effect of desvenlafaxine and duloxetine on the pharmacokinetics of the CYP2D6 probe desipramine in healthy subjects.
Patroneva A, Connolly SM, Fatato P, Pedersen R, Jiang Q, Paul J, Guico-Pabia C, Isler JA, Burczynski ME, Nichols AI.
Patroneva A, et al.
Drug Metab Dispos. 2008 Dec;36(12):2484-91. doi: 10.1124/dmd.108.021527. Epub 2008 Sep 22.
Drug Metab Dispos. 2008.
PMID: 18809731
Clinical Trial.
Item in Clipboard
The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults.
Nichols AI, Fatato P, Shenouda M, Paul J, Isler JA, Pedersen RD, Jiang Q, Ahmed S, Patroneva A.
Nichols AI, et al.
J Clin Pharmacol. 2009 Feb;49(2):219-28. doi: 10.1177/0091270008326716. Epub 2008 Nov 11.
J Clin Pharmacol. 2009.
PMID: 19001559
Clinical Trial.
Item in Clipboard
Cytochrome P450 2D6 phenotype predicts antidepressant efficacy of venlafaxine: a secondary analysis of 4 studies in major depressive disorder.
Lobello KW, Preskorn SH, Guico-Pabia CJ, Jiang Q, Paul J, Nichols AI, Patroneva A, Ninan PT.
Lobello KW, et al.
J Clin Psychiatry. 2010 Nov;71(11):1482-7. doi: 10.4088/JCP.08m04773blu. Epub 2010 Apr 6.
J Clin Psychiatry. 2010.
PMID: 20441720
Clinical Trial.
Item in Clipboard
Effect of an ATP-sensitive potassium channel opener in subjects with overactive bladder: a randomized, double-blind, placebo-controlled study (ZD0947IL/0004).
Chapple CR, Patroneva A, Raines SR.
Chapple CR, et al.
Eur Urol. 2006 May;49(5):879-86. doi: 10.1016/j.eururo.2006.01.037. Epub 2006 Feb 24.
Eur Urol. 2006.
PMID: 16517051
Clinical Trial.
Item in Clipboard
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