Plun-Favreau H - Search Results

1

Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway?

Fitzgerald JC, Plun-Favreau H. Fitzgerald JC, et al. FEBS J. 2008 Dec;275(23):5758-66. doi: 10.1111/j.1742-4658.2008.06708.x. FEBS J. 2008. PMID: 19021753 Free article. Review.

2

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

Plun-Favreau H, Klupsch K, Moisoi N, Gandhi S, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N, Wood NW, Martins LM, Downward J. Plun-Favreau H, et al. Nat Cell Biol. 2007 Nov;9(11):1243-52. doi: 10.1038/ncb1644. Epub 2007 Sep 30. Nat Cell Biol. 2007. PMID: 17906618

3

What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?

Plun-Favreau H, Gandhi S, Wood-Kaczmar A, Deas E, Yao Z, Wood NW. Plun-Favreau H, et al. Ann N Y Acad Sci. 2008 Dec;1147:30-6. doi: 10.1196/annals.1427.032. Ann N Y Acad Sci. 2008. PMID: 19076428

4

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.

Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. Gandhi S, et al. Mol Cell. 2009 Mar 13;33(5):627-38. doi: 10.1016/j.molcel.2009.02.013. Mol Cell. 2009. PMID: 19285945 Free PMC article.

5

PINK1 function in health and disease.

Deas E, Plun-Favreau H, Wood NW. Deas E, et al. EMBO Mol Med. 2009 Jun;1(3):152-65. doi: 10.1002/emmm.200900024. EMBO Mol Med. 2009. PMID: 20049715 Free PMC article. Review.

6

Mitophagy and Parkinson's disease: the PINK1-parkin link.

Deas E, Wood NW, Plun-Favreau H. Deas E, et al. Biochim Biophys Acta. 2011 Apr;1813(4):623-33. doi: 10.1016/j.bbamcr.2010.08.007. Epub 2010 Aug 21. Biochim Biophys Acta. 2011. PMID: 20736035 Free PMC article. Review.

7

PINK1 cleavage at position A103 by the mitochondrial protease PARL.

Deas E, Plun-Favreau H, Gandhi S, Desmond H, Kjaer S, Loh SH, Renton AE, Harvey RJ, Whitworth AJ, Martins LM, Abramov AY, Wood NW. Deas E, et al. Hum Mol Genet. 2011 Mar 1;20(5):867-79. doi: 10.1093/hmg/ddq526. Epub 2010 Dec 6. Hum Mol Genet. 2011. PMID: 21138942 Free PMC article.

8

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.

Fitzgerald JC, Camprubi MD, Dunn L, Wu HC, Ip NY, Kruger R, Martins LM, Wood NW, Plun-Favreau H. Fitzgerald JC, et al. Cell Death Differ. 2012 Feb;19(2):257-66. doi: 10.1038/cdd.2011.90. Epub 2011 Jun 24. Cell Death Differ. 2012. PMID: 21701498 Free PMC article.

9

Parkinson's disease and cancer: two wars, one front.

Devine MJ, Plun-Favreau H, Wood NW. Devine MJ, et al. Nat Rev Cancer. 2011 Oct 24;11(11):812-23. doi: 10.1038/nrc3150. Nat Rev Cancer. 2011. PMID: 22020207 Review.

10

Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease.

Yao Z, Gandhi S, Burchell VS, Plun-Favreau H, Wood NW, Abramov AY. Yao Z, et al. J Cell Sci. 2011 Dec 15;124(Pt 24):4194-202. doi: 10.1242/jcs.088260. Epub 2012 Jan 5. J Cell Sci. 2011. PMID: 22223879 Free PMC article.

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