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The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.
Collombat P, Hecksher-Sørensen J, Broccoli V, Krull J, Ponte I, Mundiger T, Smith J, Gruss P, Serup P, Mansouri A. Collombat P, et al. Among authors: broccoli v. Development. 2005 Jul;132(13):2969-80. doi: 10.1242/dev.01870. Epub 2005 Jun 1. Development. 2005. PMID: 15930104
Aristaless-related homeobox gene, the gene responsible for West syndrome and related disorders, is a Groucho/transducin-like enhancer of split dependent transcriptional repressor.
McKenzie O, Ponte I, Mangelsdorf M, Finnis M, Colasante G, Shoubridge C, Stifani S, Gécz J, Broccoli V. McKenzie O, et al. Among authors: broccoli v. Neuroscience. 2007 Apr 25;146(1):236-47. doi: 10.1016/j.neuroscience.2007.01.038. Epub 2007 Feb 27. Neuroscience. 2007. PMID: 17331656
Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation.
Colombo E, Collombat P, Colasante G, Bianchi M, Long J, Mansouri A, Rubenstein JL, Broccoli V. Colombo E, et al. Among authors: broccoli v. J Neurosci. 2007 Apr 25;27(17):4786-98. doi: 10.1523/JNEUROSCI.0417-07.2007. J Neurosci. 2007. PMID: 17460091 Free PMC article.
The homeobox gene Arx is a novel positive regulator of embryonic myogenesis.
Biressi S, Messina G, Collombat P, Tagliafico E, Monteverde S, Benedetti L, Cusella De Angelis MG, Mansouri A, Ferrari S, Tajbakhsh S, Broccoli V, Cossu G. Biressi S, et al. Among authors: broccoli v. Cell Death Differ. 2008 Jan;15(1):94-104. doi: 10.1038/sj.cdd.4402230. Epub 2007 Oct 12. Cell Death Differ. 2008. PMID: 17932502
153 results