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Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications.
J Med Chem. 2008 Nov 13;51(21):7010-4. doi: 10.1021/jm8009316. Epub 2008 Oct 16.
J Med Chem. 2008.
PMID: 18921992
Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production.
Hu LY, Lei HJ, Du D, Johnson TR, Fedij V, Kostlan C, Yue WS, Lovdahl M, Li JJ, Carroll M, Dettling D, Asbill J, Fan C, Wade K, Pocalyko D, Lapham K, Yalamanchili R, Samas B, Vrieze D, Ciotti S, Krieger-Burke T, Sliskovic D, Welgus H.
Hu LY, et al. Among authors: asbill j.
Bioorg Med Chem Lett. 2007 Oct 15;17(20):5693-7. doi: 10.1016/j.bmcl.2007.07.059. Epub 2007 Aug 19.
Bioorg Med Chem Lett. 2007.
PMID: 17766112
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Peptide inhibitors of alpha-amylase based on tendamistat: development of analogues with omega-amino acids linking critical binding segments.
Heyl DL, Tobwala S, Lucas LS, Nandanie AD, Himm RW, Kappler HJ, Blaney EJ, Groom J, Asbill J, Nzoma JK, Jarosz C, Palamma H, Schullery SE.
Heyl DL, et al. Among authors: asbill j.
Protein Pept Lett. 2005 Apr;12(3):275-80. doi: 10.2174/0929866053587110.
Protein Pept Lett. 2005.
PMID: 15777278
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