Gómez-Lechón MJ - Search Results

1

Inhibition of human P450 enzymes by natural extracts used in traditional medicine.

Rodeiro I, Donato MT, Jimenez N, Garrido G, Molina-Torres J, Menendez R, Castell JV, Gómez-Lechón MJ. Rodeiro I, et al. Phytother Res. 2009 Feb;23(2):279-82. doi: 10.1002/ptr.2613. Phytother Res. 2009. PMID: 18844254

2

In vitro modulation of the cytochrome P450 and ABCB1/P-glycoprotein activities of the aqueous extract of Allophylus cominia (L) Sw. leaves.

Pérez CL, Donato MT, Hernández I, Paz Lopes MT, Marrero E, Herrera JA, Gómez-Lechón MJ, Rodeiro I. Pérez CL, et al. Among authors: gomez lechon mj. Drug Metab Pers Ther. 2017 Dec 20;32(4):201-208. doi: 10.1515/dmpt-2017-0020. Drug Metab Pers Ther. 2017. PMID: 29176019

3

An update on metabolism studies using human hepatocytes in primary culture.

Gómez-Lechón MJ, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):837-54. doi: 10.1517/17425255.4.7.837. Expert Opin Drug Metab Toxicol. 2008. PMID: 18624674 Review.

4

Cytochrome p450 and steatosis.

Gómez-Lechón MJ, Jover R, Donato MT. Gómez-Lechón MJ, et al. Curr Drug Metab. 2009 Sep;10(7):692-9. doi: 10.2174/138920009789895543. Curr Drug Metab. 2009. PMID: 19702532 Review.

5

Evaluation of cytochrome P450 activities in human hepatocytes in vitro.

Gómez-Lechón MJ, Lahoz A, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Methods Mol Biol. 2012;806:87-97. doi: 10.1007/978-1-61779-367-7_7. Methods Mol Biol. 2012. PMID: 22057447

6

The use of hepatocytes to investigate drug toxicity.

Gómez-Lechón MJ, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Methods Mol Biol. 2010;640:389-415. doi: 10.1007/978-1-60761-688-7_21. Methods Mol Biol. 2010. PMID: 20645064

7

Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach.

Castell JV, Donato MT, Gómez-Lechón MJ. Castell JV, et al. Exp Toxicol Pathol. 2005 Jul;57 Suppl 1:189-204. doi: 10.1016/j.etp.2005.05.008. Exp Toxicol Pathol. 2005. PMID: 16092727 Review.

8

Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.

Gómez-Lechón MJ, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Chem Biol Interact. 2007 May 20;168(1):30-50. doi: 10.1016/j.cbi.2006.10.013. Epub 2006 Nov 28. Chem Biol Interact. 2007. PMID: 17134688 Review.

9

Human hepatic cell cultures: in vitro and in vivo drug metabolism.

Gómez-Lechón MJ, Donato T, Ponsoda X, Castell JV. Gómez-Lechón MJ, et al. Altern Lab Anim. 2003 May-Jun;31(3):257-65. doi: 10.1177/026119290303100307. Altern Lab Anim. 2003. PMID: 15612868

10

Evaluation of drug-metabolizing and functional competence of human hepatocytes incubated under hypothermia in different media for clinical infusion.

Gómez-Lechón MJ, Lahoz A, Jiménez N, Bonora A, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Cell Transplant. 2008;17(8):887-97. doi: 10.3727/096368908786576534. Cell Transplant. 2008. PMID: 19069632 Free article.

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