Holt IJ - Search Results

1

The conserved translocase Tim17 prevents mitochondrial DNA loss.

Iacovino M, Granycome C, Sembongi H, Bokori-Brown M, Butow RA, Holt IJ, Bateman JM. Iacovino M, et al. Among authors: holt ij. Hum Mol Genet. 2009 Jan 1;18(1):65-74. doi: 10.1093/hmg/ddn313. Epub 2008 Sep 30. Hum Mol Genet. 2009. PMID: 18826960 Free PMC article.

2

The yeast Holliday junction resolvase, CCE1, can restore wild-type mitochondrial DNA to human cells carrying rearranged mitochondrial DNA.

Sembongi H, Di Re M, Bokori-Brown M, Holt IJ. Sembongi H, et al. Among authors: holt ij. Hum Mol Genet. 2007 Oct 1;16(19):2306-14. doi: 10.1093/hmg/ddm182. Epub 2007 Jul 31. Hum Mol Genet. 2007. PMID: 17666405

3

Systematic segregation to mutant mitochondrial DNA and accompanying loss of mitochondrial DNA in human NT2 teratocarcinoma Cybrids.

Turner CJ, Granycome C, Hurst R, Pohler E, Juhola MK, Juhola MI, Jacobs HT, Sutherland L, Holt IJ. Turner CJ, et al. Among authors: holt ij. Genetics. 2005 Aug;170(4):1879-85. doi: 10.1534/genetics.105.043653. Epub 2005 Jun 8. Genetics. 2005. PMID: 15944344 Free PMC article.

4

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number.

Tyynismaa H, Sembongi H, Bokori-Brown M, Granycome C, Ashley N, Poulton J, Jalanko A, Spelbrink JN, Holt IJ, Suomalainen A. Tyynismaa H, et al. Among authors: holt ij. Hum Mol Genet. 2004 Dec 15;13(24):3219-27. doi: 10.1093/hmg/ddh342. Epub 2004 Oct 27. Hum Mol Genet. 2004. PMID: 15509589

5

Expression of algal nuclear ATP synthase subunit 6 in human cells results in protein targeting to mitochondria but no assembly into ATP synthase.

Bokori-Brown M, Holt IJ. Bokori-Brown M, et al. Among authors: holt ij. Rejuvenation Res. 2006 Winter;9(4):455-69. doi: 10.1089/rej.2006.9.455. Rejuvenation Res. 2006. PMID: 17105386

6

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

He J, Cooper HM, Reyes A, Di Re M, Sembongi H, Litwin TR, Gao J, Neuman KC, Fearnley IM, Spinazzola A, Walker JE, Holt IJ. He J, et al. Among authors: holt ij. Nucleic Acids Res. 2012 Jul;40(13):6109-21. doi: 10.1093/nar/gks266. Epub 2012 Mar 26. Nucleic Acids Res. 2012. PMID: 22453275 Free PMC article.

7

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication.

Fusté JM, Wanrooij S, Jemt E, Granycome CE, Cluett TJ, Shi Y, Atanassova N, Holt IJ, Gustafsson CM, Falkenberg M. Fusté JM, et al. Among authors: holt ij. Mol Cell. 2010 Jan 15;37(1):67-78. doi: 10.1016/j.molcel.2009.12.021. Mol Cell. 2010. PMID: 20129056 Free article.

8

Mammalian mitochondrial nucleoids: organizing an independently minded genome.

Holt IJ, He J, Mao CC, Boyd-Kirkup JD, Martinsson P, Sembongi H, Reyes A, Spelbrink JN. Holt IJ, et al. Mitochondrion. 2007 Sep;7(5):311-21. doi: 10.1016/j.mito.2007.06.004. Epub 2007 Jul 4. Mitochondrion. 2007. PMID: 17698423 Review.

9

Actin and myosin contribute to mammalian mitochondrial DNA maintenance.

Reyes A, He J, Mao CC, Bailey LJ, Di Re M, Sembongi H, Kazak L, Dzionek K, Holmes JB, Cluett TJ, Harbour ME, Fearnley IM, Crouch RJ, Conti MA, Adelstein RS, Walker JE, Holt IJ. Reyes A, et al. Among authors: holt ij. Nucleic Acids Res. 2011 Jul;39(12):5098-108. doi: 10.1093/nar/gkr052. Epub 2011 Mar 11. Nucleic Acids Res. 2011. PMID: 21398640 Free PMC article.

10

Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA.

Malena A, Loro E, Di Re M, Holt IJ, Vergani L. Malena A, et al. Among authors: holt ij. Hum Mol Genet. 2009 Sep 15;18(18):3407-16. doi: 10.1093/hmg/ddp281. Epub 2009 Jun 27. Hum Mol Genet. 2009. PMID: 19561330

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