Meleddu R - Search Results

1

2-Acylhydrazino-5-arylpyrrole derivatives: synthesis and antifungal activity evaluation.

Onnis V, De Logu A, Cocco MT, Fadda R, Meleddu R, Congiu C. Onnis V, et al. Among authors: meleddu r. Eur J Med Chem. 2009 Mar;44(3):1288-95. doi: 10.1016/j.ejmech.2008.08.003. Epub 2008 Aug 22. Eur J Med Chem. 2009. PMID: 18809229

2

1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings.

Biava M, Porretta GC, Poce G, De Logu A, Saddi M, Meleddu R, Manetti F, De Rossi E, Botta M. Biava M, et al. Among authors: meleddu r. J Med Chem. 2008 Jun 26;51(12):3644-8. doi: 10.1021/jm701560p. J Med Chem. 2008. PMID: 18494459

3

Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis.

Castagnolo D, De Logu A, Radi M, Bechi B, Manetti F, Magnani M, Supino S, Meleddu R, Chisu L, Botta M. Castagnolo D, et al. Among authors: meleddu r. Bioorg Med Chem. 2008 Sep 15;16(18):8587-91. doi: 10.1016/j.bmc.2008.08.016. Epub 2008 Aug 7. Bioorg Med Chem. 2008. PMID: 18752962 Free article.

4

Novel N-aryl- and N-heteryl phenazine-1-carboxamides as potential agents for the treatment of infections sustained by drug-resistant and multidrug-resistant Mycobacterium tuberculosis.

De Logu A, Palchykovska LH, Kostina VH, Sanna A, Meleddu R, Chisu L, Alexeeva IV, Shved AD. De Logu A, et al. Among authors: meleddu r. Int J Antimicrob Agents. 2009 Mar;33(3):223-9. doi: 10.1016/j.ijantimicag.2008.09.016. Epub 2008 Dec 13. Int J Antimicrob Agents. 2009. PMID: 19070992

5

Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis.

Castagnolo D, Radi M, Dessì F, Manetti F, Saddi M, Meleddu R, De Logu A, Botta M. Castagnolo D, et al. Among authors: meleddu r. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2203-5. doi: 10.1016/j.bmcl.2009.02.101. Epub 2009 Feb 28. Bioorg Med Chem Lett. 2009. PMID: 19299129

6

Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones.

Castagnolo D, Manetti F, Radi M, Bechi B, Pagano M, De Logu A, Meleddu R, Saddi M, Botta M. Castagnolo D, et al. Among authors: meleddu r. Bioorg Med Chem. 2009 Aug 1;17(15):5716-21. doi: 10.1016/j.bmc.2009.05.058. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19581099 Free article.

7

1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation.

Biava M, Porretta GC, Poce G, De Logu A, Meleddu R, De Rossi E, Manetti F, Botta M. Biava M, et al. Among authors: meleddu r. Eur J Med Chem. 2009 Nov;44(11):4734-8. doi: 10.1016/j.ejmech.2009.06.005. Epub 2009 Jun 13. Eur J Med Chem. 2009. PMID: 19595488

8

Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.

Maccioni E, Alcaro S, Orallo F, Cardia MC, Distinto S, Costa G, Yanez M, Sanna ML, Vigo S, Meleddu R, Secci D. Maccioni E, et al. Among authors: meleddu r. Eur J Med Chem. 2010 Oct;45(10):4490-8. doi: 10.1016/j.ejmech.2010.07.009. Epub 2010 Jul 17. Eur J Med Chem. 2010. PMID: 20702005

9

3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B.

Maccioni E, Alcaro S, Cirilli R, Vigo S, Cardia MC, Sanna ML, Meleddu R, Yanez M, Costa G, Casu L, Matyus P, Distinto S. Maccioni E, et al. Among authors: meleddu r. J Med Chem. 2011 Sep 22;54(18):6394-8. doi: 10.1021/jm2002876. Epub 2011 Aug 17. J Med Chem. 2011. PMID: 21777011

10

Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.

Distinto S, Yáñez M, Alcaro S, Cardia MC, Gaspari M, Sanna ML, Meleddu R, Ortuso F, Kirchmair J, Markt P, Bolasco A, Wolber G, Secci D, Maccioni E. Distinto S, et al. Among authors: meleddu r. Eur J Med Chem. 2012 Feb;48:284-95. doi: 10.1016/j.ejmech.2011.12.027. Epub 2011 Dec 24. Eur J Med Chem. 2012. PMID: 22222137

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