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Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.
Lisco A, Vanpouille C, Tchesnokov EP, Grivel JC, Biancotto A, Brichacek B, Elliott J, Fromentin E, Shattock R, Anton P, Gorelick R, Balzarini J, McGuigan C, Derudas M, Götte M, Schinazi RF, Margolis L. Lisco A, et al. Among authors: grivel jc. Cell Host Microbe. 2008 Sep 11;4(3):260-270. doi: 10.1016/j.chom.2008.07.008. Cell Host Microbe. 2008. PMID: 18779052 Free PMC article.
A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.
Vanpouille C, Lisco A, Derudas M, Saba E, Grivel JC, Brichacek B, Scrimieri F, Schinazi R, Schols D, McGuigan C, Balzarini J, Margolis L. Vanpouille C, et al. Among authors: grivel jc. J Infect Dis. 2010 Feb 15;201(4):635-43. doi: 10.1086/650343. J Infect Dis. 2010. PMID: 20085496 Free PMC article.
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.
Vanpouille C, Lisco A, Introini A, Grivel JC, Munawwar A, Merbah M, Schinazi RF, Derudas M, McGuigan C, Balzarini J, Margolis L. Vanpouille C, et al. Among authors: grivel jc. Antimicrob Agents Chemother. 2012 May;56(5):2604-11. doi: 10.1128/AAC.05986-11. Epub 2012 Feb 6. Antimicrob Agents Chemother. 2012. PMID: 22314523 Free PMC article.
Contrasting roles for TLR ligands in HIV-1 pathogenesis.
Brichacek B, Vanpouille C, Kiselyeva Y, Biancotto A, Merbah M, Hirsch I, Lisco A, Grivel JC, Margolis L. Brichacek B, et al. Among authors: grivel jc. PLoS One. 2010 Sep 20;5(9):e12831. doi: 10.1371/journal.pone.0012831. PLoS One. 2010. PMID: 20862220 Free PMC article.
113 results