Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells.
Al-Nedawi K, Meehan B, Micallef J, Lhotak V, May L, Guha A, Rak J.
Al-Nedawi K, et al. Among authors: may l.
Nat Cell Biol. 2008 May;10(5):619-24. doi: 10.1038/ncb1725. Epub 2008 Apr 20.
Nat Cell Biol. 2008.
PMID: 18425114
Aggressive human brain tumours (gliomas) often express a truncated and oncogenic form of the epidermal growth factor receptor, known as EGFRvIII. Within each tumour only a small percentage of glioma cells may actually express EGFRvIII; however, most of the cells exhibit a …
Aggressive human brain tumours (gliomas) often express a truncated and oncogenic form of the epidermal growth factor receptor, known as EGFR …