Iwai K - Search Results

1

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains.

Sato Y, Yoshikawa A, Yamagata A, Mimura H, Yamashita M, Ookata K, Nureki O, Iwai K, Komada M, Fukai S. Sato Y, et al. Among authors: iwai k. Nature. 2008 Sep 18;455(7211):358-62. doi: 10.1038/nature07254. Epub 2008 Aug 31. Nature. 2008. PMID: 18758443

2

E3 ubiquitin ligase that recognizes sugar chains.

Yoshida Y, Chiba T, Tokunaga F, Kawasaki H, Iwai K, Suzuki T, Ito Y, Matsuoka K, Yoshida M, Tanaka K, Tai T. Yoshida Y, et al. Among authors: iwai k. Nature. 2002 Jul 25;418(6896):438-42. doi: 10.1038/nature00890. Nature. 2002. PMID: 12140560

3

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

Tenno T, Fujiwara K, Tochio H, Iwai K, Morita EH, Hayashi H, Murata S, Hiroaki H, Sato M, Tanaka K, Shirakawa M. Tenno T, et al. Among authors: iwai k. Genes Cells. 2004 Oct;9(10):865-75. doi: 10.1111/j.1365-2443.2004.00780.x. Genes Cells. 2004. PMID: 15461659 Free article.

4

A ubiquitin ligase complex assembles linear polyubiquitin chains.

Kirisako T, Kamei K, Murata S, Kato M, Fukumoto H, Kanie M, Sano S, Tokunaga F, Tanaka K, Iwai K. Kirisako T, et al. Among authors: iwai k. EMBO J. 2006 Oct 18;25(20):4877-87. doi: 10.1038/sj.emboj.7601360. Epub 2006 Sep 28. EMBO J. 2006. PMID: 17006537 Free PMC article.

5

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.

Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, Akira S, Takao T, Tanaka K, Iwai K. Tokunaga F, et al. Among authors: iwai k. Nat Cell Biol. 2009 Feb;11(2):123-32. doi: 10.1038/ncb1821. Epub 2009 Jan 11. Nat Cell Biol. 2009. PMID: 19136968

6

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex.

Sato Y, Fujita H, Yoshikawa A, Yamashita M, Yamagata A, Kaiser SE, Iwai K, Fukai S. Sato Y, et al. Among authors: iwai k. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20520-5. doi: 10.1073/pnas.1109088108. Epub 2011 Dec 2. Proc Natl Acad Sci U S A. 2011. PMID: 22139374 Free PMC article.

7

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.

Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O. Tokunaga F, et al. Among authors: iwai k. EMBO J. 2012 Oct 3;31(19):3856-70. doi: 10.1038/emboj.2012.241. Epub 2012 Aug 28. EMBO J. 2012. PMID: 23032187 Free PMC article.

8

The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates.

Morimoto D, Walinda E, Fukada H, Sou YS, Kageyama S, Hoshino M, Fujii T, Tsuchiya H, Saeki Y, Arita K, Ariyoshi M, Tochio H, Iwai K, Namba K, Komatsu M, Tanaka K, Shirakawa M. Morimoto D, et al. Among authors: iwai k. Nat Commun. 2015 Jan 20;6:6116. doi: 10.1038/ncomms7116. Nat Commun. 2015. PMID: 25600778 Free PMC article.

9

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F. Nakazawa S, et al. Among authors: iwai k. Nat Commun. 2016 Aug 24;7:12547. doi: 10.1038/ncomms12547. Nat Commun. 2016. PMID: 27552911 Free PMC article.

10

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.

Yamanaka K, Ishikawa H, Megumi Y, Tokunaga F, Kanie M, Rouault TA, Morishima I, Minato N, Ishimori K, Iwai K. Yamanaka K, et al. Among authors: iwai k. Nat Cell Biol. 2003 Apr;5(4):336-40. doi: 10.1038/ncb952. Nat Cell Biol. 2003. PMID: 12629548

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