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Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics.
Bioorg Med Chem Lett. 2008 Nov 15;18(22):5904-8. doi: 10.1016/j.bmcl.2008.07.114. Epub 2008 Jul 31.
Bioorg Med Chem Lett. 2008.
PMID: 18752944
Free PMC article.
Unexpected stereochemical tolerance for the biological activity of tyroscherin.
Tae HS, Hines J, Schneekloth AR, Crews CM.
Tae HS, et al. Among authors: schneekloth ar.
Bioorg Med Chem. 2011 Mar 1;19(5):1708-13. doi: 10.1016/j.bmc.2011.01.027. Epub 2011 Jan 19.
Bioorg Med Chem. 2011.
PMID: 21315614
Free PMC article.
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Identification and characterization of a peptidic ligand for Ras.
Gareiss PC, Schneekloth AR, Salcius MJ, Seo SY, Crews CM.
Gareiss PC, et al. Among authors: schneekloth ar.
Chembiochem. 2010 Mar 1;11(4):517-22. doi: 10.1002/cbic.200900547.
Chembiochem. 2010.
PMID: 20082398
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Total synthesis and biological evaluation of tyroscherin.
Tae HS, Hines J, Schneekloth AR, Crews CM.
Tae HS, et al. Among authors: schneekloth ar.
Org Lett. 2010 Oct 1;12(19):4308-11. doi: 10.1021/ol101801u.
Org Lett. 2010.
PMID: 20831175
Free PMC article.
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Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.
Neklesa TK, Tae HS, Schneekloth AR, Stulberg MJ, Corson TW, Sundberg TB, Raina K, Holley SA, Crews CM.
Neklesa TK, et al. Among authors: schneekloth ar.
Nat Chem Biol. 2011 Jul 3;7(8):538-43. doi: 10.1038/nchembio.597.
Nat Chem Biol. 2011.
PMID: 21725302
Free PMC article.
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