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Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Jo DG, Arumugam TV, Woo HN, Park JS, Tang SC, Mughal M, Hyun DH, Park JH, Choi YH, Gwon AR, Camandola S, Cheng A, Cai H, Song W, Markesbery WR, Mattson MP. Jo DG, et al. Among authors: park jh, park js. Neurobiol Aging. 2010 Jun;31(6):917-25. doi: 10.1016/j.neurobiolaging.2008.07.003. Epub 2008 Aug 8. Neurobiol Aging. 2010. PMID: 18687504 Free PMC article.
Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.
Gwon AR, Park JS, Arumugam TV, Kwon YK, Chan SL, Kim SH, Baik SH, Yang S, Yun YK, Choi Y, Kim S, Tang SC, Hyun DH, Cheng A, Dann CE 3rd, Bernier M, Lee J, Markesbery WR, Mattson MP, Jo DG. Gwon AR, et al. Among authors: park js. Aging Cell. 2012 Aug;11(4):559-68. doi: 10.1111/j.1474-9726.2012.00817.x. Epub 2012 Apr 9. Aging Cell. 2012. PMID: 22404891 Free PMC article.
Alzheimer's disease and Notch signaling.
Woo HN, Park JS, Gwon AR, Arumugam TV, Jo DG. Woo HN, et al. Among authors: park js. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1093-7. doi: 10.1016/j.bbrc.2009.10.093. Epub 2009 Oct 22. Biochem Biophys Res Commun. 2009. PMID: 19853579 Review.
Selenium attenuates A beta production and A beta-induced neuronal death.
Gwon AR, Park JS, Park JH, Baik SH, Jeong HY, Hyun DH, Park KW, Jo DG. Gwon AR, et al. Among authors: park jh, park kw, park js. Neurosci Lett. 2010 Jan 29;469(3):391-5. doi: 10.1016/j.neulet.2009.12.035. Epub 2009 Dec 22. Neurosci Lett. 2010. PMID: 20026385
Contribution of gamma-secretase to calcium-mediated cell death.
Choi YH, Gwon AR, Jeong HY, Park JS, Baik SH, Arumugam TV, Jo DG. Choi YH, et al. Among authors: park js. Neurosci Lett. 2010 Jan 29;469(3):425-8. doi: 10.1016/j.neulet.2009.12.043. Epub 2009 Dec 23. Neurosci Lett. 2010. PMID: 20035833
Secretases as therapeutic targets for Alzheimer's disease.
Woo HN, Baik SH, Park JS, Gwon AR, Yang S, Yun YK, Jo DG. Woo HN, et al. Among authors: park js. Biochem Biophys Res Commun. 2011 Jan 7;404(1):10-5. doi: 10.1016/j.bbrc.2010.11.132. Epub 2010 Dec 3. Biochem Biophys Res Commun. 2011. PMID: 21130746 Review.
Inhibition of notch signalling ameliorates experimental inflammatory arthritis.
Park JS, Kim SH, Kim K, Jin CH, Choi KY, Jang J, Choi Y, Gwon AR, Baik SH, Yun UJ, Chae SY, Lee S, Kang YM, Lee KC, Arumugam TV, Mattson MP, Park JH, Jo DG. Park JS, et al. Among authors: park jh. Ann Rheum Dis. 2015 Jan;74(1):267-74. doi: 10.1136/annrheumdis-2013-203467. Epub 2013 Nov 19. Ann Rheum Dis. 2015. PMID: 24255545
Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
Shin MK, Kim HG, Baek SH, Jung WR, Park DI, Park JS, Jo DG, Kim KL. Shin MK, et al. Among authors: park js, park di. Neurobiol Aging. 2014 May;35(5):990-1001. doi: 10.1016/j.neurobiolaging.2013.10.091. Epub 2013 Oct 29. Neurobiol Aging. 2014. PMID: 24268884
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
Bahn G, Park JS, Yun UJ, Lee YJ, Choi Y, Park JS, Baek SH, Choi BY, Cho YS, Kim HK, Han J, Sul JH, Baik SH, Lim J, Wakabayashi N, Bae SH, Han JW, Arumugam TV, Mattson MP, Jo DG. Bahn G, et al. Among authors: park js. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12516-12523. doi: 10.1073/pnas.1819541116. Epub 2019 Jun 4. Proc Natl Acad Sci U S A. 2019. PMID: 31164420 Free PMC article.
7,071 results