ATP binding to the first nucleotide-binding domain of multidrug resistance protein MRP1 increases binding and hydrolysis of ATP and trapping of ADP at the second domain.
Hou YX, Cui L, Riordan JR, Chang XB.
Hou YX, et al. Among authors: cui l.
J Biol Chem. 2002 Feb 15;277(7):5110-9. doi: 10.1074/jbc.M107133200. Epub 2001 Dec 7.
J Biol Chem. 2002.
PMID: 11741902
Free article.
How events at these two domains are coordinated during the transport cycle have not been fully elucidated. Earlier reports (Gao, M., Cui, H. R., Loe, D. W., Grant, C. E., Almquist, K. C., Cole, S. P., and Deeley, R. G. (2000) J. Biol. Chem. 275, 13098-13108; Hou, Y., Cu …
How events at these two domains are coordinated during the transport cycle have not been fully elucidated. Earlier reports (Gao, M., Cui …