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The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover.
Aleksandrov L, Aleksandrov AA, Chang XB, Riordan JR. Aleksandrov L, et al. Among authors: aleksandrov aa. J Biol Chem. 2002 May 3;277(18):15419-25. doi: 10.1074/jbc.M111713200. Epub 2002 Feb 22. J Biol Chem. 2002. PMID: 11861646 Free article.
., and Sarkadi, B. (1999) J. Biol. Chem. 274, 12209-12212; Aleksandrov, L., Mengos, A., Chang, X., Aleksandrov, A., and Riordan, J. ...In contrast, at NBD2, MgN(3)ATP is hydrolyzed as rapidly as it is bound and the nucleoside diphosphate hydrolysis pro …
., and Sarkadi, B. (1999) J. Biol. Chem. 274, 12209-12212; Aleksandrov, L., Mengos, A., Chang, X., Aleksandrov, A …
Domain interdependence in the biosynthetic assembly of CFTR.
Cui L, Aleksandrov L, Chang XB, Hou YX, He L, Hegedus T, Gentzsch M, Aleksandrov A, Balch WE, Riordan JR. Cui L, et al. Among authors: aleksandrov l, aleksandrov a. J Mol Biol. 2007 Jan 26;365(4):981-94. doi: 10.1016/j.jmb.2006.10.086. Epub 2006 Nov 10. J Mol Biol. 2007. PMID: 17113596
Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating.
He L, Aleksandrov AA, Serohijos AW, Hegedus T, Aleksandrov LA, Cui L, Dokholyan NV, Riordan JR. He L, et al. Among authors: aleksandrov la, aleksandrov aa. J Biol Chem. 2008 Sep 26;283(39):26383-90. doi: 10.1074/jbc.M803894200. Epub 2008 Jul 25. J Biol Chem. 2008. PMID: 18658148 Free PMC article.
The cystic fibrosis transmembrane conductance regulator (CFTR) is a unique ATP-binding cassette (ABC) ion channel mutated in patients with cystic fibrosis. ...W., Hegedus, T., Aleksandrov, A. A., He, L., Cui, L., Dokholyan, N. V., and Riordan, J. ...
The cystic fibrosis transmembrane conductance regulator (CFTR) is a unique ATP-binding cassette (ABC) ion channel mutated in patients …
681 results