Targets for AD treatment: conflicting messages from γ-secretase inhibitors.
Sambamurti K, Greig NH, Utsuki T, Barnwell EL, Sharma E, Mazell C, Bhat NR, Kindy MS, Lahiri DK, Pappolla MA.
Sambamurti K, et al.
J Neurochem. 2011 May;117(3):359-74. doi: 10.1111/j.1471-4159.2011.07213.x. Epub 2011 Mar 15.
J Neurochem. 2011.
PMID: 21320126
Free PMC article.
We have previously proposed that inhibition of gamma-secretase may impair membrane recycling causing neurodegeneration starting at synapses (Sambamurti K., Suram A., Venugopal C., Prakasam A., Zhou Y., Lahiri D. K. and Greig N. H. A partial failure of membran …
We have previously proposed that inhibition of gamma-secretase may impair membrane recycling causing neurodegeneration starting at synapses …