Solá RJ - Search Results

1

Effects of glycosylation on the stability of protein pharmaceuticals.

Solá RJ, Griebenow K. Solá RJ, et al. J Pharm Sci. 2009 Apr;98(4):1223-45. doi: 10.1002/jps.21504. J Pharm Sci. 2009. PMID: 18661536 Free PMC article. Review.

2

Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications.

Solá RJ, Rodríguez-Martínez JA, Griebenow K. Solá RJ, et al. Cell Mol Life Sci. 2007 Aug;64(16):2133-52. doi: 10.1007/s00018-007-6551-y. Cell Mol Life Sci. 2007. PMID: 17558468 Review.

3

Chemical glycosylation: new insights on the interrelation between protein structural mobility, thermodynamic stability, and catalysis.

Solá RJ, Griebenow K. Solá RJ, et al. FEBS Lett. 2006 Mar 6;580(6):1685-90. doi: 10.1016/j.febslet.2006.02.001. Epub 2006 Feb 17. FEBS Lett. 2006. PMID: 16494868 Free article.

4

Engineering of protein thermodynamic, kinetic, and colloidal stability: Chemical Glycosylation with monofunctionally activated glycans.

Solá RJ, Al-Azzam W, Griebenow K. Solá RJ, et al. Biotechnol Bioeng. 2006 Aug 20;94(6):1072-9. doi: 10.1002/bit.20933. Biotechnol Bioeng. 2006. PMID: 16586505

5

Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy.

Solá RJ, Griebenow K. Solá RJ, et al. BioDrugs. 2010 Feb 1;24(1):9-21. doi: 10.2165/11530550-000000000-00000. BioDrugs. 2010. PMID: 20055529 Free PMC article. Review.

6

Moisture-induced solid state instabilities in alpha-chymotrypsin and their reduction through chemical glycosylation.

Flores-Fernández GM, Pagán M, Almenas M, Solá RJ, Griebenow K. Flores-Fernández GM, et al. Among authors: sola rj. BMC Biotechnol. 2010 Aug 9;10:57. doi: 10.1186/1472-6750-10-57. BMC Biotechnol. 2010. PMID: 20696067 Free PMC article.

7

Influence of modulated structural dynamics on the kinetics of alpha-chymotrypsin catalysis. Insights through chemical glycosylation, molecular dynamics and domain motion analysis.

Solá RJ, Griebenow K. Solá RJ, et al. FEBS J. 2006 Dec;273(23):5303-19. doi: 10.1111/j.1742-4658.2006.05524.x. Epub 2006 Oct 31. FEBS J. 2006. PMID: 17076704 Free article.

Here we investigate whether alpha-CT's structural dynamics directly influence the kinetics of enzyme catalysis. Chemical glycosylation [Sola RJ & Griebenow K (2006) FEBS Lett 580, 1685-1690] was used to generate a series of glycosylated alpha-CT conjugates with …

Here we investigate whether alpha-CT's structural dynamics directly influence the kinetics of enzyme catalysis. Chemical glycosylation [S …

8

Effect of PEG modification on subtilisin Carlsberg activity, enantioselectivity, and structural dynamics in 1,4-dioxane.

Castillo B, Solá RJ, Ferrer A, Barletta G, Griebenow K. Castillo B, et al. Among authors: sola rj. Biotechnol Bioeng. 2008 Jan 1;99(1):9-17. doi: 10.1002/bit.21510. Biotechnol Bioeng. 2008. PMID: 17546684

9

Stabilization of alpha-chymotrypsin upon PEGylation correlates with reduced structural dynamics.

Rodríguez-Martínez JA, Solá RJ, Castillo B, Cintrón-Colón HR, Rivera-Rivera I, Barletta G, Griebenow K. Rodríguez-Martínez JA, et al. Among authors: sola rj. Biotechnol Bioeng. 2008 Dec 15;101(6):1142-9. doi: 10.1002/bit.22014. Biotechnol Bioeng. 2008. PMID: 18781698 Free PMC article.

10

On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg.

Pagán M, Solá RJ, Griebenow K. Pagán M, et al. Among authors: sola rj. Biotechnol Bioeng. 2009 May 1;103(1):77-84. doi: 10.1002/bit.22221. Biotechnol Bioeng. 2009. PMID: 19132746 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

18 results

Search Page