Mueller SO - Search Results

1

Primary hepatocytes as a model to analyze species-specific toxicity and drug metabolism.

Tuschl G, Lauer B, Mueller SO. Tuschl G, et al. Among authors: mueller so. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):855-70. doi: 10.1517/17425255.4.7.855. Expert Opin Drug Metab Toxicol. 2008. PMID: 18624675 Review.

2

Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression.

Tuschl G, Mueller SO. Tuschl G, et al. Among authors: mueller so. Toxicology. 2006 Feb 1;218(2-3):205-15. doi: 10.1016/j.tox.2005.10.017. Epub 2005 Dec 6. Toxicology. 2006. PMID: 16337326

3

Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes.

Lauer B, Tuschl G, Kling M, Mueller SO. Lauer B, et al. Among authors: mueller so. Chem Biol Interact. 2009 Apr 15;179(1):17-24. doi: 10.1016/j.cbi.2008.10.031. Epub 2008 Oct 31. Chem Biol Interact. 2009. PMID: 19022234

4

Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: a valuable model for in vitro toxicity and drug-drug interaction studies.

Tuschl G, Hrach J, Walter Y, Hewitt PG, Mueller SO. Tuschl G, et al. Among authors: mueller so. Chem Biol Interact. 2009 Sep 14;181(1):124-37. doi: 10.1016/j.cbi.2009.05.015. Epub 2009 May 29. Chem Biol Interact. 2009. PMID: 19482013

5

Species-specific activation of nuclear receptors correlates with the response of liver drug metabolizing enzymes to EMD 392949 in vitro.

Mueller SO, Fery Y, Tuschl G, Schrenk D. Mueller SO, et al. Toxicol Lett. 2010 Mar 1;193(1):120-3. doi: 10.1016/j.toxlet.2009.12.014. Epub 2009 Dec 24. Toxicol Lett. 2010. PMID: 20035846

6

Alternatives in pharmaceutical toxicology: global and focussed approaches--two case studies.

Mueller SO, Tuschl G, Kling M. Mueller SO, et al. ALTEX. 2007;24(2):117-24. doi: 10.14573/altex.2007.2.117. ALTEX. 2007. PMID: 17728977 Free article.

7

Understanding the biokinetics of ibuprofen after single and repeated treatments in rat and human in vitro liver cell systems.

Truisi GL, Consiglio ED, Parmentier C, Savary CC, Pomponio G, Bois F, Lauer B, Jossé R, Hewitt PG, Mueller SO, Richert L, Guillouzo A, Testai E. Truisi GL, et al. Among authors: mueller so. Toxicol Lett. 2015 Mar 4;233(2):172-86. doi: 10.1016/j.toxlet.2015.01.006. Epub 2015 Jan 8. Toxicol Lett. 2015. PMID: 25578229 Free article.

8

Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro.

Richert L, Tuschl G, Viollon-Abadie C, Blanchard N, Bonet A, Heyd B, Halkic N, Wimmer E, Dolgos H, Mueller SO. Richert L, et al. Among authors: mueller so. Drug Metab Dispos. 2008 Apr;36(4):702-14. doi: 10.1124/dmd.107.018358. Epub 2008 Jan 23. Drug Metab Dispos. 2008. PMID: 18216275

9

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.

Godoy P, Hengstler JG, Ilkavets I, Meyer C, Bachmann A, Müller A, Tuschl G, Mueller SO, Dooley S. Godoy P, et al. Among authors: mueller so. Hepatology. 2009 Jun;49(6):2031-43. doi: 10.1002/hep.22880. Hepatology. 2009. PMID: 19274752

10

Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.

Richert L, Tuschl G, Abadie C, Blanchard N, Pekthong D, Mantion G, Weber JC, Mueller SO. Richert L, et al. Among authors: mueller so. Toxicol Appl Pharmacol. 2009 Feb 15;235(1):86-96. doi: 10.1016/j.taap.2008.11.019. Epub 2008 Dec 10. Toxicol Appl Pharmacol. 2009. PMID: 19118567

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