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New opportunities with the Duff reaction.
Masurier N, Moreau E, Lartigue C, Gaumet V, Chezal JM, Heitz A, Teulade JC, Chavignon O. Masurier N, et al. Among authors: moreau e. J Org Chem. 2008 Aug 1;73(15):5989-92. doi: 10.1021/jo800700b. Epub 2008 Jul 3. J Org Chem. 2008. PMID: 18597528
Heterocyclization of functionalized vinylic derivatives of imidazo.
Chezal JM, Moreau E, Delmas G, Gueiffier A, Blache Y, Grassy G, Lartigue C, Chavignon O, Teulade JC. Chezal JM, et al. Among authors: moreau e. J Org Chem. 2001 Oct 5;66(20):6576-84. doi: 10.1021/jo015582x. J Org Chem. 2001. PMID: 11578207
Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.
Trzeciakiewicz A, Fortin S, Moreau E, C-Gaudreault R, Lacroix J, Chambon C, Communal Y, Chezal JM, Miot-Noirault E, Bouchon B, Degoul F. Trzeciakiewicz A, et al. Among authors: moreau e. Biochem Pharmacol. 2011 May 1;81(9):1116-23. doi: 10.1016/j.bcp.2011.02.014. Epub 2011 Mar 1. Biochem Pharmacol. 2011. PMID: 21371445 Free article.
Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity.
Masurier N, Debiton E, Jacquemet A, Bussière A, Chezal JM, Ollivier A, Tétégan D, Andaloussi M, Galmier MJ, Lacroix J, Canitrot D, Teulade JC, Gaudreault RC, Chavignon O, Moreau E. Masurier N, et al. Among authors: moreau e. Eur J Med Chem. 2012 Jun;52:137-50. doi: 10.1016/j.ejmech.2012.03.011. Epub 2012 Mar 20. Eur J Med Chem. 2012. PMID: 22503207
233 results