Harris DM - Search Results

1

GPCR signalling in hypertension: role of GRKs.

Harris DM, Cohn HI, Pesant S, Eckhart AD. Harris DM, et al. Clin Sci (Lond). 2008 Aug;115(3):79-89. doi: 10.1042/CS20070442. Clin Sci (Lond). 2008. PMID: 18593382 Review.

2

Vascular smooth muscle G(q) signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension.

Harris DM, Cohn HI, Pesant S, Zhou RH, Eckhart AD. Harris DM, et al. Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H3072-9. doi: 10.1152/ajpheart.00880.2007. Epub 2007 Sep 14. Am J Physiol Heart Circ Physiol. 2007. PMID: 17873012 Free article.

3

Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constriction.

Cohn HI, Harris DM, Pesant S, Pfeiffer M, Zhou RH, Koch WJ, Dorn GW 2nd, Eckhart AD. Cohn HI, et al. Among authors: harris dm. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1695-704. doi: 10.1152/ajpheart.00564.2008. Epub 2008 Aug 22. Am J Physiol Heart Circ Physiol. 2008. PMID: 18723764 Free PMC article.

4

G protein-coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans.

Cohn HI, Xi Y, Pesant S, Harris DM, Hyslop T, Falkner B, Eckhart AD. Cohn HI, et al. Among authors: harris dm. Hypertension. 2009 Jul;54(1):71-6. doi: 10.1161/HYPERTENSIONAHA.108.125955. Epub 2009 Jun 1. Hypertension. 2009. PMID: 19487588 Free PMC article.

5

Endothelial S100A1 modulates vascular function via nitric oxide.

Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P. Pleger ST, et al. Among authors: harris dm. Circ Res. 2008 Apr 11;102(7):786-94. doi: 10.1161/CIRCRESAHA.108.172031. Epub 2008 Feb 21. Circ Res. 2008. PMID: 18292599

6

Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.

DeGeorge BR Jr, Gao E, Boucher M, Vinge LE, Martini JS, Raake PW, Chuprun JK, Harris DM, Kim GW, Soltys S, Eckhart AD, Koch WJ. DeGeorge BR Jr, et al. Among authors: harris dm. Circulation. 2008 Mar 18;117(11):1378-87. doi: 10.1161/CIRCULATIONAHA.107.752618. Epub 2008 Mar 3. Circulation. 2008. PMID: 18316484

7

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes.

Martini JS, Raake P, Vinge LE, DeGeorge BR Jr, Chuprun JK, Harris DM, Gao E, Eckhart AD, Pitcher JA, Koch WJ. Martini JS, et al. Among authors: harris dm. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12457-62. doi: 10.1073/pnas.0803153105. Epub 2008 Aug 18. Proc Natl Acad Sci U S A. 2008. PMID: 18711143 Free PMC article.

8

Inhibition of angiotensin II Gq signaling augments beta-adrenergic receptor mediated effects in a renal artery stenosis model of high blood pressure.

Harris DM, Chen X, Pesant S, Cohn HI, MacDonnell SM, Boucher M, Vinge LE, Raake P, Moraca SR, Li D, Most P, Houser SR, Koch WJ, Eckhart AD. Harris DM, et al. J Mol Cell Cardiol. 2009 Jan;46(1):100-7. doi: 10.1016/j.yjmcc.2008.09.708. Epub 2008 Sep 30. J Mol Cell Cardiol. 2009. PMID: 18930063 Free PMC article.

9

Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.

Brinks H, Boucher M, Gao E, Chuprun JK, Pesant S, Raake PW, Huang ZM, Wang X, Qiu G, Gumpert A, Harris DM, Eckhart AD, Most P, Koch WJ. Brinks H, et al. Among authors: harris dm. Circ Res. 2010 Oct 29;107(9):1140-9. doi: 10.1161/CIRCRESAHA.110.221010. Epub 2010 Sep 2. Circ Res. 2010. PMID: 20814022 Free PMC article.

10

Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling.

Keys JR, Zhou RH, Harris DM, Druckman CA, Eckhart AD. Keys JR, et al. Among authors: harris dm. Circulation. 2005 Aug 23;112(8):1145-53. doi: 10.1161/CIRCULATIONAHA.104.531657. Epub 2005 Aug 15. Circulation. 2005. PMID: 16103237

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