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Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization.
Vettor R, Granzotto M, De Stefani D, Trevellin E, Rossato M, Farina MG, Milan G, Pilon C, Nigro A, Federspil G, Vigneri R, Vitiello L, Rizzuto R, Baratta R, Frittitta L. Vettor R, et al. Among authors: vitiello l. J Clin Endocrinol Metab. 2008 Sep;93(9):3541-50. doi: 10.1210/jc.2007-2680. Epub 2008 Jun 26. J Clin Endocrinol Metab. 2008. PMID: 18583466
The glucose-dependent insulinotropic polypeptide receptor is overexpressed amongst GNAS1 mutation-negative somatotropinomas and drives growth hormone (GH)-promoter activity in GH3 cells.
Occhi G, Losa M, Albiger N, Trivellin G, Regazzo D, Scanarini M, Monteserin-Garcia JL, Fröhlich B, Ferasin S, Terreni MR, Fassina A, Vitiello L, Stalla G, Mantero F, Scaroni C. Occhi G, et al. Among authors: vitiello l. J Neuroendocrinol. 2011 Jul;23(7):641-9. doi: 10.1111/j.1365-2826.2011.02155.x. J Neuroendocrinol. 2011. PMID: 21554434
212 results