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Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling.
Ganesh T, Min J, Thepchatri P, Du Y, Li L, Lewis I, Wilson L, Fu H, Chiosis G, Dingledine R, Liotta D, Snyder JP, Sun A. Ganesh T, et al. Among authors: thepchatri p. Bioorg Med Chem. 2008 Jul 15;16(14):6903-10. doi: 10.1016/j.bmc.2008.05.047. Epub 2008 May 27. Bioorg Med Chem. 2008. PMID: 18571929 Free PMC article.
Cancer and virus leads by HTS, chemical design and SEA data mining.
Thepchatri P, Min J, Ganesh T, Du Y, Lewis I, Kurtkaya S, Prussia A, Li L, Sneed B, Plemper RK, Fu H, Liotta DC, Snyder JP, Dingledine R, Sun A. Thepchatri P, et al. Curr Top Med Chem. 2009;9(13):1159-71. doi: 10.2174/156802609789753581. Curr Top Med Chem. 2009. PMID: 19807668 Free PMC article. Review.
Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.
Jiang J, Ganesh T, Du Y, Thepchatri P, Rojas A, Lewis I, Kurtkaya S, Li L, Qui M, Serrano G, Shaw R, Sun A, Dingledine R. Jiang J, et al. Among authors: thepchatri p. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2307-12. doi: 10.1073/pnas.0909310107. Epub 2010 Jan 14. Proc Natl Acad Sci U S A. 2010. PMID: 20080612 Free PMC article.
Asymmetric synthesis of host-directed inhibitors of myxoviruses.
Moore TW, Sana K, Yan D, Thepchatri P, Ndungu JM, Saindane MT, Lockwood MA, Natchus MG, Liotta DC, Plemper RK, Snyder JP, Sun A. Moore TW, et al. Among authors: thepchatri p. Beilstein J Org Chem. 2013;9:197-203. doi: 10.3762/bjoc.9.23. Epub 2013 Jan 30. Beilstein J Org Chem. 2013. PMID: 23400228 Free PMC article.
Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy.
Moore TW, Sana K, Yan D, Krumm SA, Thepchatri P, Snyder JP, Marengo J, Arrendale RF, Prussia AJ, Natchus MG, Liotta DC, Plemper RK, Sun A. Moore TW, et al. Among authors: thepchatri p. ACS Med Chem Lett. 2013 Aug 8;4(8):762-767. doi: 10.1021/ml400166b. ACS Med Chem Lett. 2013. PMID: 23956816 Free PMC article.
Conformations of laulimalide in DMSO-d6.
Thepchatri P, Cicero DO, Monteagudo E, Ghosh AK, Cornett B, Weeks ER, Snyder JP. Thepchatri P, et al. J Am Chem Soc. 2005 Sep 21;127(37):12838-46. doi: 10.1021/ja042890e. J Am Chem Soc. 2005. PMID: 16159277
11 results