Pawluczkowycz AW - Search Results

1

Complement activation on B lymphocytes opsonized with rituximab or ofatumumab produces substantial changes in membrane structure preceding cell lysis.

Beum PV, Lindorfer MA, Beurskens F, Stukenberg PT, Lokhorst HM, Pawluczkowycz AW, Parren PW, van de Winkel JG, Taylor RP. Beum PV, et al. Among authors: pawluczkowycz aw. J Immunol. 2008 Jul 1;181(1):822-32. doi: 10.4049/jimmunol.181.1.822. J Immunol. 2008. PMID: 18566448

2

Complement activation and C3b deposition on rituximab-opsonized cells substantially blocks binding of phycoerythrin-labeled anti-mouse IgG probes to rituximab.

Beum PV, Kennedy AD, Li Y, Pawluczkowycz AW, Williams ME, Taylor RP. Beum PV, et al. Among authors: pawluczkowycz aw. J Immunol Methods. 2004 Nov;294(1-2):37-42. doi: 10.1016/j.jim.2004.08.004. J Immunol Methods. 2004. PMID: 15604014

3

Selective and efficient inhibition of the alternative pathway of complement by a mAb that recognizes C3b/iC3b.

DiLillo DJ, Pawluczkowycz AW, Peng W, Kennedy AD, Beum PV, Lindorfer MA, Taylor RP. DiLillo DJ, et al. Among authors: pawluczkowycz aw. Mol Immunol. 2006 Mar;43(7):1010-9. doi: 10.1016/j.molimm.2005.05.003. Epub 2005 Jun 14. Mol Immunol. 2006. PMID: 15961157

4

Thrice-weekly low-dose rituximab decreases CD20 loss via shaving and promotes enhanced targeting in chronic lymphocytic leukemia.

Williams ME, Densmore JJ, Pawluczkowycz AW, Beum PV, Kennedy AD, Lindorfer MA, Hamil SH, Eggleton JC, Taylor RP. Williams ME, et al. Among authors: pawluczkowycz aw. J Immunol. 2006 Nov 15;177(10):7435-43. doi: 10.4049/jimmunol.177.10.7435. J Immunol. 2006. PMID: 17082663

5

Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models.

Li Y, Williams ME, Cousar JB, Pawluczkowycz AW, Lindorfer MA, Taylor RP. Li Y, et al. Among authors: pawluczkowycz aw. J Immunol. 2007 Sep 15;179(6):4263-71. doi: 10.4049/jimmunol.179.6.4263. J Immunol. 2007. PMID: 17785867

6

Hematin promotes complement alternative pathway-mediated deposition of C3 activation fragments on human erythrocytes: potential implications for the pathogenesis of anemia in malaria.

Pawluczkowycz AW, Lindorfer MA, Waitumbi JN, Taylor RP. Pawluczkowycz AW, et al. J Immunol. 2007 Oct 15;179(8):5543-52. doi: 10.4049/jimmunol.179.8.5543. J Immunol. 2007. PMID: 17911641

7

Binding of rituximab, trastuzumab, cetuximab, or mAb T101 to cancer cells promotes trogocytosis mediated by THP-1 cells and monocytes.

Beum PV, Mack DA, Pawluczkowycz AW, Lindorfer MA, Taylor RP. Beum PV, et al. Among authors: pawluczkowycz aw. J Immunol. 2008 Dec 1;181(11):8120-32. doi: 10.4049/jimmunol.181.11.8120. J Immunol. 2008. PMID: 19018005

8

Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX.

Pawluczkowycz AW, Beurskens FJ, Beum PV, Lindorfer MA, van de Winkel JG, Parren PW, Taylor RP. Pawluczkowycz AW, et al. J Immunol. 2009 Jul 1;183(1):749-58. doi: 10.4049/jimmunol.0900632. Epub 2009 Jun 17. J Immunol. 2009. PMID: 19535640

9

Fractionated subcutaneous rituximab is well-tolerated and preserves CD20 expression on tumor cells in patients with chronic lymphocytic leukemia.

Aue G, Lindorfer MA, Beum PV, Pawluczkowycz AW, Vire B, Hughes T, Taylor RP, Wiestner A. Aue G, et al. Among authors: pawluczkowycz aw. Haematologica. 2010 Feb;95(2):329-32. doi: 10.3324/haematol.2009.012484. Epub 2009 Aug 13. Haematologica. 2010. PMID: 19679883 Free PMC article. Clinical Trial.

10

A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement.

Lindorfer MA, Pawluczkowycz AW, Peek EM, Hickman K, Taylor RP, Parker CJ. Lindorfer MA, et al. Among authors: pawluczkowycz aw. Blood. 2010 Mar 18;115(11):2283-91. doi: 10.1182/blood-2009-09-244285. Epub 2010 Jan 12. Blood. 2010. PMID: 20068220 Free article.

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