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Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
Miller AA, Bundy GL, Mott JE, Skepner JE, Boyle TP, Harris DW, Hromockyj AE, Marotti KR, Zurenko GE, Munzner JB, Sweeney MT, Bammert GF, Hamel JC, Ford CW, Zhong WZ, Graber DR, Martin GE, Han F, Dolak LA, Seest EP, Ruble JC, Kamilar GM, Palmer JR, Banitt LS, Hurd AR, Barbachyn MR. Miller AA, et al. Among authors: barbachyn mr. Antimicrob Agents Chemother. 2008 Aug;52(8):2806-12. doi: 10.1128/AAC.00247-08. Epub 2008 Jun 2. Antimicrob Agents Chemother. 2008. PMID: 18519725 Free PMC article.
Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens.
Barbachyn MR, Cleek GJ, Dolak LA, Garmon SA, Morris J, Seest EP, Thomas RC, Toops DS, Watt W, Wishka DG, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Adams WJ, Friis JM, Slatter JG, Sams JP, Oien NL, Zaya MJ, Wienkers LC, Wynalda MA. Barbachyn MR, et al. J Med Chem. 2003 Jan 16;46(2):284-302. doi: 10.1021/jm020248u. J Med Chem. 2003. PMID: 12519066
Oxazolidinones: new antibacterial agents.
Ford CW, Hamel JC, Stapert D, Moerman JK, Hutchinson DK, Barbachyn MR, Zurenko GE. Ford CW, et al. Among authors: barbachyn mr. Trends Microbiol. 1997 May;5(5):196-200. doi: 10.1016/S0966-842X(97)01032-9. Trends Microbiol. 1997. PMID: 9160508 Review.
Carbon-carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria.
Lee CS, Allwine DA, Barbachyn MR, Grega KC, Dolak LA, Ford CW, Jensen RM, Seest EP, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Zurenko GE, Genin MJ. Lee CS, et al. Among authors: barbachyn mr. Bioorg Med Chem. 2001 Dec;9(12):3243-53. doi: 10.1016/s0968-0896(01)00233-4. Bioorg Med Chem. 2001. PMID: 11711300
26 results