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S100A8/A9 drives monocytes towards M2-like macrophage differentiation and associates with M2-like macrophages in osteoarthritic synovium.
van Kooten NJT, Blom AB, Teunissen van Manen IJ, Theeuwes WF, Roth J, Gorris MAJ, Walgreen B, Sloetjes AW, Helsen MM, Vitters EL, van Lent PLEM, Koëter S, van der Kraan PM, Vogl T, van den Bosch MHJ. van Kooten NJT, et al. Among authors: helsen mm. Rheumatology (Oxford). 2024 Jan 12:keae020. doi: 10.1093/rheumatology/keae020. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 38216750
Fibroblast Activation Protein Targeted Photodynamic Therapy Selectively Kills Activated Skin Fibroblasts from Systemic Sclerosis Patients and Prevents Tissue Contraction.
Dorst DN, van Caam APM, Vitters EL, Walgreen B, Helsen MMA, Klein C, Gudi S, Wubs T, Kumari J, Vonk MC, van der Kraan PM, Koenders MI. Dorst DN, et al. Among authors: helsen mma. Int J Mol Sci. 2021 Nov 24;22(23):12681. doi: 10.3390/ijms222312681. Int J Mol Sci. 2021. PMID: 34884484 Free PMC article.
Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis.
Kruisbergen NNL, Di Ceglie I, van Gemert Y, Walgreen B, Helsen MMA, Slöetjes AW, Koenders MI, van de Loo FAJ, Roth J, Vogl T, van der Kraan PM, Blom AB, van Lent PLEM, van den Bosch MHJ. Kruisbergen NNL, et al. Among authors: helsen mma. Antioxidants (Basel). 2021 Oct 22;10(11):1660. doi: 10.3390/antiox10111660. Antioxidants (Basel). 2021. PMID: 34829531 Free PMC article.
Targeting of fibroblast activation protein in rheumatoid arthritis patients: imaging and ex vivo photodynamic therapy.
Dorst DN, Rijpkema M, Buitinga M, Walgreen B, Helsen MMA, Brennan E, Klein C, Laverman P, Ramming A, Schmidkonz C, Kuwert T, Schett G, van der Kraan PM, Gotthardt M, Koenders MI. Dorst DN, et al. Among authors: helsen mma. Rheumatology (Oxford). 2022 Jul 6;61(7):2999-3009. doi: 10.1093/rheumatology/keab664. Rheumatology (Oxford). 2022. PMID: 34450633 Free PMC article.
Urate-induced epigenetic modifications in myeloid cells.
Badii M, Gaal OI, Cleophas MC, Klück V, Davar R, Habibi E, Keating ST, Novakovic B, Helsen MM, Dalbeth N, Stamp LK, Macartney-Coxson D, Phipps-Green AJ, Stunnenberg HG, Dinarello CA, Merriman TR, Netea MG, Crişan TO, Joosten LAB. Badii M, et al. Among authors: helsen mm. Arthritis Res Ther. 2021 Jul 28;23(1):202. doi: 10.1186/s13075-021-02580-1. Arthritis Res Ther. 2021. PMID: 34321071 Free PMC article.
A single dose of anti-IL-1β antibodies prevents Western diet-induced immune activation during early stage collagenase-induced osteoarthritis, but does not ameliorate end-stage pathology.
Kruisbergen NNL, van Gemert Y, Walgreen B, Helsen MMA, Slöetjes AW, Koenders MI, van de Loo FAJ, Roth J, Vogl T, van der Kraan PM, Blom AB, van den Bosch MHJ, van Lent PLEM. Kruisbergen NNL, et al. Among authors: helsen mma. Osteoarthritis Cartilage. 2021 Oct;29(10):1462-1473. doi: 10.1016/j.joca.2021.07.005. Epub 2021 Jul 21. Osteoarthritis Cartilage. 2021. PMID: 34298196 Free article.
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