Schuetz EG - Search Results

1

The influence of CYP3A5 genotype on dexamethasone induction of CYP3A activity in African Americans.

Roberts PJ, Rollins KD, Kashuba AD, Paine MF, Nelsen AC, Williams EE, Moran C, Lamba JK, Schuetz EG, Hawke RL. Roberts PJ, et al. Among authors: schuetz eg. Drug Metab Dispos. 2008 Aug;36(8):1465-9. doi: 10.1124/dmd.107.020065. Epub 2008 May 19. Drug Metab Dispos. 2008. PMID: 18490434 Free PMC article.

2

CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults.

Givens RC, Lin YS, Dowling AL, Thummel KE, Lamba JK, Schuetz EG, Stewart PW, Watkins PB. Givens RC, et al. Among authors: schuetz eg. J Appl Physiol (1985). 2003 Sep;95(3):1297-300. doi: 10.1152/japplphysiol.00322.2003. Epub 2003 May 16. J Appl Physiol (1985). 2003. PMID: 12754175 Free article. Clinical Trial.

3

The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation.

Isoherranen N, Ludington SR, Givens RC, Lamba JK, Pusek SN, Dees EC, Blough DK, Iwanaga K, Hawke RL, Schuetz EG, Watkins PB, Thummel KE, Paine MF. Isoherranen N, et al. Among authors: schuetz eg. Drug Metab Dispos. 2008 Jan;36(1):146-54. doi: 10.1124/dmd.107.018382. Epub 2007 Oct 22. Drug Metab Dispos. 2008. PMID: 17954524

4

The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans.

Ilic K, Hawke RL, Thirumaran RK, Schuetz EG, Hull JH, Kashuba AD, Stewart PW, Lindley CM, Chen ML. Ilic K, et al. Among authors: schuetz eg. Drug Metab Dispos. 2013 Mar;41(3):575-81. doi: 10.1124/dmd.112.048108. Epub 2012 Dec 13. Drug Metab Dispos. 2013. PMID: 23238783 Free PMC article.

5

Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.

Mouly SJ, Matheny C, Paine MF, Smith G, Lamba J, Lamba V, Pusek SN, Schuetz EG, Stewart PW, Watkins PB. Mouly SJ, et al. Among authors: schuetz eg. Clin Pharmacol Ther. 2005 Dec;78(6):605-18. doi: 10.1016/j.clpt.2005.08.014. Clin Pharmacol Ther. 2005. PMID: 16338276 Clinical Trial.

6

Genetic contribution to variable human CYP3A-mediated metabolism.

Lamba JK, Lin YS, Schuetz EG, Thummel KE. Lamba JK, et al. Among authors: schuetz eg. Adv Drug Deliv Rev. 2002 Nov 18;54(10):1271-94. doi: 10.1016/s0169-409x(02)00066-2. Adv Drug Deliv Rev. 2002. PMID: 12406645 Review.

7

Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians.

Brown KC, Hosseinipour MC, Hoskins JM, Thirumaran RK, Tien HC, Weigel R, Tauzie J, Shumba I, Lamba JK, Schuetz EG, McLeod HL, Kashuba AD, Corbett AH. Brown KC, et al. Among authors: schuetz eg. Pharmacogenomics. 2012 Jan;13(1):113-21. doi: 10.2217/pgs.11.132. Epub 2011 Nov 23. Pharmacogenomics. 2012. PMID: 22111602 Free PMC article.

8

Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.

Lamba J, Lamba V, Strom S, Venkataramanan R, Schuetz E. Lamba J, et al. Drug Metab Dispos. 2008 Jan;36(1):169-81. doi: 10.1124/dmd.107.016600. Epub 2007 Oct 9. Drug Metab Dispos. 2008. PMID: 17925385

9

Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms.

Zheng H, Webber S, Zeevi A, Schuetz E, Zhang J, Bowman P, Boyle G, Law Y, Miller S, Lamba J, Burckart GJ. Zheng H, et al. Am J Transplant. 2003 Apr;3(4):477-83. doi: 10.1034/j.1600-6143.2003.00077.x. Am J Transplant. 2003. PMID: 12694072 Free article.

10

PharmGKB summary: very important pharmacogene information for CYP3A5.

Lamba J, Hebert JM, Schuetz EG, Klein TE, Altman RB. Lamba J, et al. Among authors: schuetz eg. Pharmacogenet Genomics. 2012 Jul;22(7):555-8. doi: 10.1097/FPC.0b013e328351d47f. Pharmacogenet Genomics. 2012. PMID: 22407409 Free PMC article. No abstract available.

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