Kozma SC - Search Results

1

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

Gulati P, Gaspers LD, Dann SG, Joaquin M, Nobukuni T, Natt F, Kozma SC, Thomas AP, Thomas G. Gulati P, et al. Among authors: kozma sc. Cell Metab. 2008 May;7(5):456-65. doi: 10.1016/j.cmet.2008.03.002. Cell Metab. 2008. PMID: 18460336 Free PMC article.

2

hvps34, an ancient player, enters a growing game: mTOR Complex1/S6K1 signaling.

Nobukuni T, Kozma SC, Thomas G. Nobukuni T, et al. Among authors: kozma sc. Curr Opin Cell Biol. 2007 Apr;19(2):135-41. doi: 10.1016/j.ceb.2007.02.019. Epub 2007 Feb 23. Curr Opin Cell Biol. 2007. PMID: 17321123 Review.

3

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.

Kalender A, Selvaraj A, Kim SY, Gulati P, Brûlé S, Viollet B, Kemp BE, Bardeesy N, Dennis P, Schlager JJ, Marette A, Kozma SC, Thomas G. Kalender A, et al. Among authors: kozma sc. Cell Metab. 2010 May 5;11(5):390-401. doi: 10.1016/j.cmet.2010.03.014. Cell Metab. 2010. PMID: 20444419 Free PMC article.

4

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.

Garami A, Zwartkruis FJ, Nobukuni T, Joaquin M, Roccio M, Stocker H, Kozma SC, Hafen E, Bos JL, Thomas G. Garami A, et al. Among authors: kozma sc. Mol Cell. 2003 Jun;11(6):1457-66. doi: 10.1016/s1097-2765(03)00220-x. Mol Cell. 2003. PMID: 12820960 Free article.

5

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.

Gangloff YG, Mueller M, Dann SG, Svoboda P, Sticker M, Spetz JF, Um SH, Brown EJ, Cereghini S, Thomas G, Kozma SC. Gangloff YG, et al. Among authors: kozma sc. Mol Cell Biol. 2004 Nov;24(21):9508-16. doi: 10.1128/MCB.24.21.9508-9516.2004. Mol Cell Biol. 2004. PMID: 15485918 Free PMC article.

6

Hypothalamic mTOR signaling regulates food intake.

Cota D, Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, Seeley RJ. Cota D, et al. Among authors: kozma sc. Science. 2006 May 12;312(5775):927-30. doi: 10.1126/science.1124147. Science. 2006. PMID: 16690869

7

A liaison between mTOR signaling, ribosome biogenesis and cancer.

Gentilella A, Kozma SC, Thomas G. Gentilella A, et al. Among authors: kozma sc. Biochim Biophys Acta. 2015 Jul;1849(7):812-20. doi: 10.1016/j.bbagrm.2015.02.005. Epub 2015 Feb 28. Biochim Biophys Acta. 2015. PMID: 25735853 Free PMC article. Review.

8

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

Kozma SC, Thomas G. Kozma SC, et al. Bioessays. 2002 Jan;24(1):65-71. doi: 10.1002/bies.10031. Bioessays. 2002. PMID: 11782951 Review.

9

Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors.

Johansson G, Mahller YY, Collins MH, Kim MO, Nobukuni T, Perentesis J, Cripe TP, Lane HA, Kozma SC, Thomas G, Ratner N. Johansson G, et al. Among authors: kozma sc. Mol Cancer Ther. 2008 May;7(5):1237-45. doi: 10.1158/1535-7163.MCT-07-2335. Mol Cancer Ther. 2008. PMID: 18483311 Free PMC article.

10

mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells.

Guo F, Li J, Du W, Zhang S, O'Connor M, Thomas G, Kozma S, Zingarelli B, Pang Q, Zheng Y. Guo F, et al. Leukemia. 2013 Oct;27(10):2040-2046. doi: 10.1038/leu.2013.93. Epub 2013 Mar 29. Leukemia. 2013. PMID: 23538752 Free PMC article.

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