Groutas WC - Search Results

1

Inhibition of serine proteases by a new class of cyclosulfamide-based carbamylating agents.

Yang Q, Li Y, Dou D, Gan X, Mohan S, Groutas CS, Stevenson LE, Lai Z, Alliston KR, Zhong J, Williams TD, Groutas WC. Yang Q, et al. Among authors: groutas cs, groutas wc. Arch Biochem Biophys. 2008 Jul 15;475(2):115-20. doi: 10.1016/j.abb.2008.04.020. Epub 2008 Apr 22. Arch Biochem Biophys. 2008. PMID: 18457652 Free PMC article.

2

Inhibitors of human neutrophil cathepsin G: structural and biochemical studies.

Groutas WC, Brubaker MJ, Venkataraman R, Epp JB, Stanga MA, McClenahan JJ. Groutas WC, et al. Arch Biochem Biophys. 1992 Apr;294(1):144-6. doi: 10.1016/0003-9861(92)90148-p. Arch Biochem Biophys. 1992. PMID: 1497704

3

Enantioselective inhibition of human leukocyte elastase.

Groutas WC, Brubaker MJ, Venkataraman R, Stanga MA. Groutas WC, et al. Arch Biochem Biophys. 1992 Aug 15;297(1):144-6. doi: 10.1016/0003-9861(92)90652-d. Arch Biochem Biophys. 1992. PMID: 1637176

4

Inhibition of human leukocyte elastase by phosphate esters of N-hydroxysuccinimide and its derivatives: direct observation of a phosphorylated enzyme by 31P nuclear magnetic resonance spectroscopy.

Groutas WC, Venkataraman R, Brubaker MJ, Stanga MA. Groutas WC, et al. Biochemistry. 1991 Apr 30;30(17):4132-6. doi: 10.1021/bi00231a004. Biochemistry. 1991. PMID: 2021604

5

Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase.

Groutas WC, Stanga MA, Castrisos JC, Schatz EJ. Groutas WC, et al. J Enzyme Inhib. 1990;3(3):237-43. doi: 10.3109/14756369009035842. J Enzyme Inhib. 1990. PMID: 2079641

6

The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.

Groutas WC, Chong LS, Venkataraman R, Epp JB, Kuang R, Houser-Archield N, Hoidal JR. Groutas WC, et al. Bioorg Med Chem. 1995 Feb;3(2):187-93. doi: 10.1016/0968-0896(95)00013-7. Bioorg Med Chem. 1995. PMID: 7796053

7

Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils.

Groutas WC, Huang H, Epp JB, Venkataraman R, McClenahan JJ, Tagusagawa F. Groutas WC, et al. Biochim Biophys Acta. 1994 Nov 29;1227(3):130-6. doi: 10.1016/0925-4439(94)90087-6. Biochim Biophys Acta. 1994. PMID: 7986820

8

Efficient inhibition of human leukocyte elastase and cathepsin G by saccharin derivatives.

Groutas WC, Houser-Archield N, Chong LS, Venkataraman R, Epp JB, Huang H, McClenahan JJ. Groutas WC, et al. J Med Chem. 1993 Oct 15;36(21):3178-81. doi: 10.1021/jm00073a019. J Med Chem. 1993. PMID: 8230105

9

Novel potential mechanism-based inhibitors of human leukocyte elastase and cathepsin G: derivatives of isothiazolidin-3-one.

Groutas WC, Chong LS, Venkataraman R. Groutas WC, et al. Biochem Biophys Res Commun. 1993 Dec 15;197(2):730-9. doi: 10.1006/bbrc.1993.2540. Biochem Biophys Res Commun. 1993. PMID: 8267609

10

Substituted 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides: a new class of potential mechanism-based inhibitors of human leukocyte elastase and cathepsin G.

Groutas WC, Kuang R, Venkataraman R. Groutas WC, et al. Biochem Biophys Res Commun. 1994 Jan 14;198(1):341-9. doi: 10.1006/bbrc.1994.1048. Biochem Biophys Res Commun. 1994. PMID: 8292039

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