Brodie TA - Search Results

1

Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats.

Conway JG, Pink H, Bergquist ML, Han B, Depee S, Tadepalli S, Lin P, Crumrine RC, Binz J, Clark RL, Selph JL, Stimpson SA, Hutchins JT, Chamberlain SD, Brodie TA. Conway JG, et al. Among authors: brodie ta. J Pharmacol Exp Ther. 2008 Jul;326(1):41-50. doi: 10.1124/jpet.107.129429. Epub 2008 Apr 23. J Pharmacol Exp Ther. 2008. PMID: 18434589

2

Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases.

Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD. Conway JG, et al. Among authors: brodie ta. J Pharmacol Exp Ther. 2001 Sep;298(3):900-8. J Pharmacol Exp Ther. 2001. PMID: 11504783

3

Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel.

Li X, Bradford BU, Wheeler MD, Stimpson SA, Pink HM, Brodie TA, Schwab JH, Thurman RG. Li X, et al. Among authors: brodie ta. Infect Immun. 2001 Sep;69(9):5883-91. doi: 10.1128/IAI.69.9.5883-5891.2001. Infect Immun. 2001. PMID: 11500467 Free PMC article.

4

Early alterations in the collagen meshwork and lesions in the ankles are associated with spontaneous osteoarthritis in guinea-pigs.

Han B, Cole AA, Shen Y, Brodie T, Williams JM. Han B, et al. Osteoarthritis Cartilage. 2002 Oct;10(10):778-84. doi: 10.1053/joca.2002.0822. Osteoarthritis Cartilage. 2002. PMID: 12359163 Free article.

5

PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742.

Faiola B, Falls JG, Peterson RA, Bordelon NR, Brodie TA, Cummings CA, Romach EH, Miller RT. Faiola B, et al. Among authors: brodie ta. Toxicol Sci. 2008 Oct;105(2):384-94. doi: 10.1093/toxsci/kfn130. Epub 2008 Jun 30. Toxicol Sci. 2008. PMID: 18593727

6

CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.

Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL. Tippin TK, et al. Among authors: brodie ta. Drug Metab Dispos. 2003 Jul;31(7):870-7. doi: 10.1124/dmd.31.7.870. Drug Metab Dispos. 2003. PMID: 12814963

7

Vascular effects of GI262570X (PPAR-gamma agonist) in the brown adipose tissue of Han Wistar rats: a review of 1-month, 13-week, 27-week and 2-year oral toxicity studies.

Elangbam CS, Brodie TA, Brown HR, Nold JB, Raczniak TJ, Tyler RD, Lightfoot RM, Wall HG. Elangbam CS, et al. Among authors: brodie ta. Toxicol Pathol. 2002 Jul-Aug;30(4):420-6. doi: 10.1080/01926230290105640. Toxicol Pathol. 2002. PMID: 12187934

8

Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X.

Casey WM, Brodie T, Yoon L, Ni H, Jordan HL, Cariello NF. Casey WM, et al. Biomarkers. 2008 Jun;13(4):364-76. doi: 10.1080/13547500801903545. Biomarkers. 2008. PMID: 18484352

9

Thymic Lymphomas in a 6-Month rasH2-Tg Mouse Carcinogenicity Study With the RORγt Inverse Agonist, BMS-986251.

Haggerty HG, Sathish JG, Gleason CR, Al-Haddawi M, Brodie TA, Bonnette KL, Lewis BS, Graziano MJ. Haggerty HG, et al. Among authors: brodie ta. Toxicol Sci. 2021 Aug 30;183(1):93-104. doi: 10.1093/toxsci/kfab086. Toxicol Sci. 2021. PMID: 34240189

10

Adverse vacuolation in multiple tissues in cynomolgus monkeys following repeat-dose administration of a PEGylated protein.

Fletcher AM, Tellier P, Douville J, Mansell P, Graziano MJ, Mangipudy RS, Brodie TA, Achanzar WE. Fletcher AM, et al. Among authors: brodie ta. Toxicol Lett. 2019 Dec 15;317:120-129. doi: 10.1016/j.toxlet.2019.09.023. Epub 2019 Sep 30. Toxicol Lett. 2019. PMID: 31580884

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