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Zwitterionic CRTh2 antagonists.
Luker T, Bonnert R, Paine SW, Schmidt J, Sargent C, Cook AR, Cook A, Gardiner P, Hill S, Weyman-Jones C, Patel A, Thom S, Thorne P. Luker T, et al. Among authors: gardiner p. J Med Chem. 2011 Mar 24;54(6):1779-88. doi: 10.1021/jm1014549. Epub 2011 Feb 28. J Med Chem. 2011. PMID: 21355602
Effect on airway responsiveness of six weeks treatment with salmeterol.
Beach JR, Young CL, Harkawat R, Gardiner PV, Avery AJ, Coward GA, Walters EH, Hendrick DJ. Beach JR, et al. Among authors: gardiner pv. Pulm Pharmacol. 1993 Jun;6(2):155-7. doi: 10.1006/pulp.1993.1020. Pulm Pharmacol. 1993. PMID: 8102918 Clinical Trial.
Cathepsin C inhibitors: property optimization and identification of a clinical candidate.
Furber M, Tiden AK, Gardiner P, Mete A, Ford R, Millichip I, Stein L, Mather A, Kinchin E, Luckhurst C, Barber S, Cage P, Sanganee H, Austin R, Chohan K, Beri R, Thong B, Wallace A, Oreffo V, Hutchinson R, Harper S, Debreczeni J, Breed J, Wissler L, Edman K. Furber M, et al. Among authors: gardiner p. J Med Chem. 2014 Mar 27;57(6):2357-67. doi: 10.1021/jm401705g. Epub 2014 Mar 14. J Med Chem. 2014. PMID: 24592859
Dipeptidyl Peptidase 1 Inhibitor AZD7986 Induces a Sustained, Exposure-Dependent Reduction in Neutrophil Elastase Activity in Healthy Subjects.
Palmér R, Mäenpää J, Jauhiainen A, Larsson B, Mo J, Russell M, Root J, Prothon S, Chialda L, Forte P, Egelrud T, Stenvall K, Gardiner P. Palmér R, et al. Among authors: gardiner p. Clin Pharmacol Ther. 2018 Dec;104(6):1155-1164. doi: 10.1002/cpt.1053. Epub 2018 Apr 16. Clin Pharmacol Ther. 2018. PMID: 29484635 Free PMC article. Clinical Trial.
AZD5634, an inhaled ENaC inhibitor, in healthy subjects and patients with cystic fibrosis.
Kristensson C, Åstrand A, Donaldson S, Goldwater R, Abdulai R, Patel N, Gardiner P, Tehler U, Mercier AK, Olsson M, Ersdal E, Mäenpää J, Bramer T, Malmgren A, Bennett W, Keen C. Kristensson C, et al. Among authors: gardiner p. J Cyst Fibros. 2022 Jul;21(4):684-690. doi: 10.1016/j.jcf.2022.02.010. Epub 2022 Feb 26. J Cyst Fibros. 2022. PMID: 35227647 Free article. Clinical Trial.
689 results