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Taming the PI3K team to hold inflammation and cancer at bay.
Hirsch E, Ciraolo E, Ghigo A, Costa C. Hirsch E, et al. Among authors: ghigo a. Pharmacol Ther. 2008 May;118(2):192-205. doi: 10.1016/j.pharmthera.2008.02.004. Epub 2008 Mar 5. Pharmacol Ther. 2008. PMID: 18420279 Review.
MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation.
Schirone L, Vecchio D, Valenti V, Forte M, Relucenti M, Angelini A, Zaglia T, Schiavon S, D'Ambrosio L, Sarto G, Stanzione R, Mangione E, Miglietta S, Di Bona A, Fedrigo M, Ghigo A, Versaci F, Petrozza V, Marchitti S, Rubattu S, Volpe M, Sadoshima J, Frati L, Frati G, Sciarretta S. Schirone L, et al. Among authors: ghigo a. Cell Mol Life Sci. 2023 Aug 11;80(9):245. doi: 10.1007/s00018-023-04877-7. Cell Mol Life Sci. 2023. PMID: 37566283 Free PMC article.
Duality of Nrf2 in iron-overload cardiomyopathy.
Federti E, Vinchi F, Iatcenko I, Ghigo A, Matte A, Toya SCM, Siciliano A, Chiabrando D, Tolosano E, Vance SZ, Riccardi V, Andolfo I, Iezzi M, Lamolinara A, Iolascon A, De Franceschi L. Federti E, et al. Among authors: ghigo a. Haematologica. 2023 May 1;108(5):1335-1348. doi: 10.3324/haematol.2022.281995. Haematologica. 2023. PMID: 36700398 Free PMC article.
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.
Perino A, Ghigo A, Ferrero E, Morello F, Santulli G, Baillie GS, Damilano F, Dunlop AJ, Pawson C, Walser R, Levi R, Altruda F, Silengo L, Langeberg LK, Neubauer G, Heymans S, Lembo G, Wymann MP, Wetzker R, Houslay MD, Iaccarino G, Scott JD, Hirsch E. Perino A, et al. Among authors: ghigo a. Mol Cell. 2011 Apr 8;42(1):84-95. doi: 10.1016/j.molcel.2011.01.030. Mol Cell. 2011. PMID: 21474070 Free PMC article.
125 results